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Start Over Author "B, Graffin" Journal annales de dermatologie et de venereologie
5 results on '"B, Graffin"'

1. [Scabby and hemorrhagic rhinitis]

Author

T, Boyé, B, Graffin, B, Fournier, B, Guennoc, J-P, Terrier, and F, Carsuzaa

Subjects
Diagnosis, Differential, Nail Diseases, Fusarium, Mycoses, Sepsis, Granulomatosis with Polyangiitis, Humans, Female, Hemorrhage, Endocarditis, Bacterial, Aged, Rhinitis
Published
2005

2. [Pemphigoid and acquired hemophilia]

Author

E, Lightburn, J J, Morand, B, Graffin, S, Molinier, G, Raphenon, P, Poullin, J R, Harlé, and C, Chouc

Subjects
Male, Factor VIII, Pemphigoid, Bullous, Immunization, Passive, Humans, Factor VII, Hemophilia A, Immunosuppressive Agents, Recombinant Proteins, Aged, Autoantibodies
Abstract

The association of bullous pemphigoid and acquired haemophilia is reported.A 74 year-old man developed a bullous pemphigoid after decreasing corticotherapy, ecchymosis and haematomas revealing a high level of acquired anti-VIII antibodies (110 Bethesda UB units; TCA 98 s). Immunosuppressive treatment (cyclosporine, prednisone, azathioprine and bolus of cyclophosphamide) did not stop the disease. Perfusion of recombinant factor VIIa, human immunoglobulins and prednisone-azathioprine association permitted clinical and biological remission.Acquired haemophilia is idiopathic half the time. It can appear in autoimmmune diseases. Mortality is high. Only 4 cases of association with bullous pemphigoid have been reported in the literature. At the haemorrhagic phase, porcine factor VIII or more recombinant activated factor VII with human immunoglobulins are necessary. Immunosuppressive treatment is used to decrease production of anti-factor VIII antibodies.

Published
2002

3. Rhinite croûteuse et hémorragique

Author

F. Carsuzaa, B. Graffin, B. Fournier, J.-P. Terrier, B. Guennoc, and T. Boye

Subjects
Autoimmune disease, Systemic disease, medicine.medical_specialty, Vascular disease, business.industry, Wegener granulomatosis, medicine, Dermatology, medicine.disease, business, Vasculitis, Connective tissue disease
Published
2005
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4. [Scabby and hemorrhagic rhinitis].

Author

Boyé T, Graffin B, Fournier B, Guennoc B, Terrier JP, and Carsuzaa F

Subjects
Aged, Diagnosis, Differential, Endocarditis, Bacterial complications, Endocarditis, Bacterial diagnosis, Female, Fusarium pathogenicity, Humans, Mycoses complications, Mycoses diagnosis, Nail Diseases etiology, Nail Diseases pathology, Rhinitis complications, Rhinitis etiology, Sepsis complications, Sepsis diagnosis, Granulomatosis with Polyangiitis complications, Granulomatosis with Polyangiitis diagnosis, Hemorrhage etiology, Rhinitis pathology
Published
2005
Full Text
View/download PDF

5. [Pemphigoid and acquired hemophilia].

Author

Lightburn E, Morand JJ, Graffin B, Molinier S, Raphenon G, Poullin P, Harlé JR, and Chouc C

Subjects
Aged, Autoantibodies blood, Factor VII therapeutic use, Hemophilia A drug therapy, Hemophilia A immunology, Humans, Immunization, Passive, Immunosuppressive Agents administration & dosage, Male, Pemphigoid, Bullous drug therapy, Pemphigoid, Bullous immunology, Recombinant Proteins therapeutic use, Factor VIII immunology, Hemophilia A complications, Pemphigoid, Bullous complications
Abstract

Introduction: The association of bullous pemphigoid and acquired haemophilia is reported., Case-Report: A 74 year-old man developed a bullous pemphigoid after decreasing corticotherapy, ecchymosis and haematomas revealing a high level of acquired anti-VIII antibodies (110 Bethesda UB units; TCA 98 s). Immunosuppressive treatment (cyclosporine, prednisone, azathioprine and bolus of cyclophosphamide) did not stop the disease. Perfusion of recombinant factor VIIa, human immunoglobulins and prednisone-azathioprine association permitted clinical and biological remission., Discussion: Acquired haemophilia is idiopathic half the time. It can appear in autoimmmune diseases. Mortality is high. Only 4 cases of association with bullous pemphigoid have been reported in the literature. At the haemorrhagic phase, porcine factor VIII or more recombinant activated factor VII with human immunoglobulins are necessary. Immunosuppressive treatment is used to decrease production of anti-factor VIII antibodies.

Published
2001

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