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Your search keyword '"Kim, Jun Young"' showing total 24 results
Start Over Author "Kim, Jun Young" Journal annals of dermatology
24 results on '"Kim, Jun Young"'

4. Participants' Satisfaction with the Atopic Dermatitis Education Program: Assessing the Impact of Each Content Using Structural Equation Modeling

Author

Ryoo, Ji Hoon, primary, Lee, Seon Hwa, additional, Lee, Hyun Ji, additional, Park, Joonsoo, additional, Kim, Sung-Ae, additional, Ryoo, Young Wook, additional, Shin, Dong Hoon, additional, Suh, Moo Kyu, additional, Kim, Jun Young, additional, Park, Kyung Duck, additional, Lee, Weon Ju, additional, Lee, Seok-Jong, additional, Kim, Do Won, additional, and Jang, Yong Hyun, additional

Published
2021
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8. Increased Expression of Interleukin-12 in Lesional Skin of Atopic Dermatitis Patients with Psoriasiform Features on Histopathology: An Immunohistochemical Study

Author

Lim, Hyun Jung, primary, Han, Man-Hoon, additional, Lee, Eun Hye, additional, Eun, Dong Hyuk, additional, Kim, Jun Young, additional, Lee, Weon Ju, additional, Lee, Seok-Jong, additional, Kim, Do Won, additional, Park, Tae-In, additional, Kim, Sang-Hyun, additional, and Jang, Yong Hyun, additional

Published
2020
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22. Emerging Perspectives of YAP/TAZ in Human Skin Epidermal and Dermal Aging.

Author

Kim JY and Quan T

Abstract

Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ) are key downstream effectors of the Hippo signaling pathway, which plays a central role in tissue homeostasis, organ development, and regeneration. While the dysregulation of YAP/TAZ has been linked to various human diseases, their involvement in the aging of human skin has only recently begun to manifest. In the skin, the YAP/TAZ effectors emerge as central regulators in maintaining homeostasis of epidermal stem cells and dermal extracellular matrix, and thus intimately linked to skin aging processes. This review underscores recent molecular breakthroughs highlighting how age-related decline of YAP/TAZ activity impacts human epidermal and dermal aging. Gaining insight into the evolving roles of YAP/TAZ in human skin aging presents a promising avenue for the development of innovative therapeutic approaches aimed at enhancing skin health and addressing age-related skin conditions., Competing Interests: The authors have nothing to disclose., (© 2024 The Korean Dermatological Association and The Korean Society for Investigative Dermatology.)

Published
2024
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24. Potential Immunoinflammatory Role of Staphylococcal Enterotoxin A in Atopic Dermatitis: Immunohistopathological Analysis and in vitro Assay.

Author

Lee HW, Kim SM, Kim JM, Oh BM, Kim JY, Jung HJ, Lim HJ, Kim BS, Lee WJ, Lee SJ, and Kim DW

Abstract

Background: The underlying mechanism of atopic dermatitis (AD) exacerbated by Staphylococcus aureus has not been established. However, we demonstrated recently that the majority of S. aureus strains colonized in the skin of Korean AD patients carried genes encoding staphylococcal enterotoxin A (SEA) and/or toxic shock syndrome toxin-1 (TSST-1)., Objective: To clarify the role of staphylococcal superantigen, SEA in AD., Methods: With the lesional skin of 9 AD patients and normal looking skin of one healthy adult, we examined first the expression of SEA, staphylococcal enterotoxin B (SEB), and TSST-1 using immunohistochemical analysis. In addition, we investigated the effects of SEA on the expression of inflammation-related adhesion molecules and cytokines in human HaCaT keratinocytes and Human Umbilical Vein Endothelial Cells (HUVECs) by reverse transcriptase-polymerase chain reaction (RT-PCR) analysis and enzyme-linked immunosorbent assay., Results: Staphylococcal protein A (SPA) and SEA were detected with increased immunoreactivity in AD patients. However, TSST-1 showed mild-to-moderate immunoreactivity in AD patients, whereas SEB was minimally detected. In the double immunofluorescence investigation, SEA and SPA were well co-localized. SEA induced upregulation of adhesion molecules and elicited inflammatory responses in HaCaT keratinocytes and HUVECs., Conclusion: This study demonstrates the importance of SEA as an immunoinflammatory triggering factor of AD in Koreans.

Published
2013
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