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A best evidence topic has been constructed using a described protocol. The three-part question addressed was: In patients who underwent appendicectomy for uncomplicated appendicitis is the use of postoperative antibiotics associated with lower rates of surgical site infections? The search has been devised and 6 studies were deemed to be suitable to answer the question. The outcome assessed was the efficiency of postoperative antibiotic therapy in decreasing the rate of surgical site infections in uncomplicated appendicitis. Authors recommend against the use of postoperative antibiotics based on the supported evidence. Hence, its usage was not associated with lower rates of surgical site infections. On the contrary, it might increase the cost, postoperative morbidity and length of stay.

A best evidence topic has been constructed using a described protocol. The three-part question addressed was: does the anastomotic technique after ileocolic resection affects the recurrence rate in patients with Crohn's disease? Using OVID interface and PubMed interface, 16 articles were found; out of this 6 studies were deemed to be suitable to answer the question. The outcomes assessed were anastomotic recurrence rate. The best evidence showed that Kono-S ileocolic anastomotic technique is associated with significantly low recurrence rate in patient with Crohn's disease., Highlights • Kono-S ileocolic anastomotic technique. • Low recurrence rate. • Crohn's disease.

A best evidence topic has been constructed using a described protocol. The three-part question addressed was: in patient with Whipple's procedure which anastomotic technique has lower leak rate pancreaticogastostomy (PG) or pancreatojejunostomy (PJ)? Using the reported search, 38 articles were found; out of this six studies were deemed to be suitable to answer the question. The outcomes assessed were incidence of anastomotic leaks (pancreatic fistula) in both techniques PG and PJ. In conclusion, the best evidence showed that PG anastomosis has lower incidence of pancreatic fistula in comparison to PJ anastomosis., Highlights • Aim: Comparison of pancreatic fistula rate among pancreaticogastostomy (PG) vs pancreatojejunostomy (PJ) anastomosis. • Result: Six randomized controlled trials were included. • Conclusion: The best evidence showed that PG anastomosis has lower incidence of pancreatic fistula than PJ anastomosis.