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Your search keyword '"Rossini, Paolo"' showing total 14 results
Start Over Author "Rossini, Paolo" Journal annals of neurology
14 results on '"Rossini, Paolo"'

2. Six‐Month Assessment of a Hand Prosthesis with Intraneural Tactile Feedback

Author

Petrini, Francesco M., primary, Valle, Giacomo, additional, Strauss, Ivo, additional, Granata, Giuseppe, additional, Di Iorio, Riccardo, additional, D'Anna, Edoardo, additional, Čvančara, Paul, additional, Mueller, Matthias, additional, Carpaneto, Jacopo, additional, Clemente, Francesco, additional, Controzzi, Marco, additional, Bisoni, Lorenzo, additional, Carboni, Caterina, additional, Barbaro, Massimo, additional, Iodice, Francesco, additional, Andreu, David, additional, Hiairrassary, Arthur, additional, Divoux, Jean‐Louis, additional, Cipriani, Christian, additional, Guiraud, David, additional, Raffo, Luigi, additional, Fernandez, Eduardo, additional, Stieglitz, Thomas, additional, Raspopovic, Stanisa, additional, Rossini, Paolo M., additional, and Micera, Silvestro, additional

Published
2018
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3. Sustainable method for Alzheimer dementia prediction in mild cognitive impairment: Electroencephalographic connectivity and graph theory combined with apolipoprotein E

Author

Vecchio, Fabrizio, primary, Miraglia, Francesca, additional, Iberite, Francesco, additional, Lacidogna, Giordano, additional, Guglielmi, Valeria, additional, Marra, Camillo, additional, Pasqualetti, Patrizio, additional, Tiziano, Francesco Danilo, additional, and Rossini, Paolo Maria, additional

Published
2018
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4. The electroencephalographic fingerprint of sleep is genetically determined: A twin study

Author

De Gennaro, Luigi, primary, Marzano, Cristina, additional, Fratello, Fabiana, additional, Moroni, Fabio, additional, Pellicciari, Maria Concetta, additional, Ferlazzo, Fabio, additional, Costa, Stefania, additional, Couyoumdjian, Alessandro, additional, Curcio, Giuseppe, additional, Sforza, Emilia, additional, Malafosse, Alain, additional, Finelli, Luca A., additional, Pasqualetti, Patrizio, additional, Ferrara, Michele, additional, Bertini, Mario, additional, and Rossini, Paolo Maria, additional

Published
2008
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6. Apolipoprotein E and alpha brain rhythms in mild cognitive impairment: A multicentric Electroencephalogram study

Author

Babiloni, Claudio, primary, Benussi, Luisa, additional, Binetti, Giuliano, additional, Cassetta, Emanuele, additional, Dal Forno, Gloria, additional, Del Percio, Claudio, additional, Ferreri, Florinda, additional, Ferri, Raffaele, additional, Frisoni, Giovanni, additional, Ghidoni, Roberta, additional, Miniussi, Carlo, additional, Rodriguez, Guido, additional, Romani, Gian Luca, additional, Squitti, Rosanna, additional, Ventriglia, Maria Carla, additional, and Rossini, Paolo M., additional

Published
2005
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7. Atypical dementia associated with a novel presenilin‐2 mutation

Author

Binetti, Giuliano, primary, Signorini, Simona, additional, Squitti, Rosanna, additional, Alberici, Antonella, additional, Benussi, Luisa, additional, Cassetta, Emanuele, additional, Battista Frisoni, Giovanni, additional, Barbiero, Laura, additional, Feudatari, Enrica, additional, Nicosia, Francesca, additional, Testa, Cristina, additional, Zanetti, Orazio, additional, Gennarelli, Massimo, additional, Perani, Daniela, additional, Anchisi, Davide, additional, Ghidoni, Roberta, additional, and Rossini, Paolo Maria, additional

Published
2003
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12. Apolipoprotein E and alpha brain rhythms in mild cognitive impairment: A multicentric Electroencephalogram study

Author

Babiloni, Claudio, Benussi, Luisa, Binetti, Giuliano, Cassetta, Emanuele, Dal Forno, Gloria, Del Percio, Claudio, Ferreri, Florinda, Ferri, Raffaele, Frisoni, Giovanni, Ghidoni, Roberta, Miniussi, Carlo, Rodriguez, Guido, Romani, Gian Luca, Squitti, Rosanna, Ventriglia, Maria Carla, and Rossini, Paolo M.

Abstract

Relationships between the apolipoprotein E ε4 allele and electroencephalographic (EEG) rhythmicity have been demonstrated in Alzheimer's disease (AD) patients but not in the preclinical stage prodromic to it, namely, mild cognitive impairment (MCI). The present multicentric EEG study tested the hypothesis that presence of ε4 affects sources of resting EEG rhythms in both MCI and AD subjects. We enrolled 89 MCI subjects (34.8% with ε4) and 103 AD patients (50.4% with ε4). Resting eyes‐closed EEG data were recorded for all subjects. EEG rhythms of interest were delta (2—4Hz), theta (4–8Hz), alpha 1 (8–10.5Hz), alpha 2 (10.5–13Hz), beta 1 (13–20Hz), and beta 2 (20–30Hz). EEG cortical sources were estimated by low‐resolution brain electromagnetic tomography. Results showed that amplitude of alpha 1 and 2 sources in occipital, temporal, and limbic areas was lower in subjects carrying the ε4 allele than in those not carrying the ε4 allele (p< 0.01). This was true for both MCI and AD. For the first time to our knowledge, a relationship was shown between ApoE genotype and global neurophysiological phenotype (ie, cortical alpha rhythmicity) in a preclinical AD condition, MCI, in addition to clinically manifest AD. Such a demonstration motivates future genotype–EEG phenotype studies for the early prediction of AD conversion in individual MCI subjects. Ann Neurol 2005

Published
2006
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13. Motor cortex excitability in Alzheimer's disease: A transcranial magnetic stimulation study

Author

Ferreri, Florinda, Pauri, Flavia, Pasqualetti, Patrizio, Fini, Rita, Dal Forno, Gloria, and Rossini, Paolo Maria

Abstract

Motor deficits affect patients with Alzheimer's disease only at later stages. Recent studies demonstrate that the primary motor cortex is affected by neuronal degeneration accompanied by the formation of amyloid plaques and neurofibrillary tangles. It is conceivable that neuronal loss is compensated by reorganization of the neural circuitries occurring along the natural course of the disease, thereby maintaining motor performances in daily living. Cortical motor output to upper limbs was tested via motor‐evoked potentials from forearm and hand muscles elicited by transcranial magnetic stimulation of motor cortex in 16 patients with mild Alzheimer's disease without motor deficits. Motor cortex excitability was increased, and the center of gravity of motor cortical output, as represented by excitable scalp sites, showed a frontal and medial shift, without correlated changes in the site of maximal excitability (hot‐spot). This may indicate functional reorganization, possibly after the neuronal loss in motor areas. Hyperexcitability might be caused by a dysregulation of the intracortical GABAergic inhibitory circuitries and selective alteration of glutamatergic neurotransmission. Such findings suggest that motor cortex hyperexcitability and reorganization allows prolonged preservation of motor function during the clinical course of Alzheimer's disease.

Published
2003
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14. Six-Month Assessment of a Hand Prosthesis with Intraneural Tactile Feedback.

Author

Petrini FM, Valle G, Strauss I, Granata G, Di Iorio R, D'Anna E, Čvančara P, Mueller M, Carpaneto J, Clemente F, Controzzi M, Bisoni L, Carboni C, Barbaro M, Iodice F, Andreu D, Hiairrassary A, Divoux JL, Cipriani C, Guiraud D, Raffo L, Fernandez E, Stieglitz T, Raspopovic S, Rossini PM, and Micera S

Subjects
Adult, Amputation, Traumatic physiopathology, Female, Hand innervation, Humans, Male, Middle Aged, Time Factors, Amputation, Traumatic rehabilitation, Artificial Limbs, Feedback, Sensory physiology, Hand physiology, Implantable Neurostimulators, Touch physiology
Abstract

Objective: Hand amputation is a highly disabling event, which significantly affects quality of life. An effective hand replacement can be achieved if the user, in addition to motor functions, is provided with the sensations that are naturally perceived while grasping and moving. Intraneural peripheral electrodes have shown promising results toward the restoration of the sense of touch. However, the long-term usability and clinical relevance of intraneural sensory feedback have not yet been clearly demonstrated., Methods: To this aim, we performed a 6-month clinical study with 3 transradial amputees who received implants of transverse intrafascicular multichannel electrodes (TIMEs) in their median and ulnar nerves. After calibration, electrical stimulation was delivered through the TIMEs connected to artificial sensors in the digits of a prosthesis to generate sensory feedback, which was then used by the subjects while performing different grasping tasks., Results: All subjects, notwithstanding their important clinical differences, reported stimulation-induced sensations from the phantom hand for the whole duration of the trial. They also successfully integrated the sensory feedback into their motor control strategies while performing experimental tests simulating tasks of real life (with and without the support of vision). Finally, they reported a decrement of their phantom limb pain and a general improvement in mood state., Interpretation: The promising results achieved with all subjects show the feasibility of the use of intraneural stimulation in clinical settings. ANN NEUROL 2019;85:137-154., (© 2018 American Neurological Association.)

Published
2019
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