1. Rosai-Dorfman Disease
- Author
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Joe Baroud, Ghassan Abu Sittah, Fadi Ghieh, and Reem Karami
- Subjects
Adult ,Male ,medicine.medical_specialty ,Lymphadenopathy ,Disease ,030230 surgery ,Risk Assessment ,Severity of Illness Index ,03 medical and health sciences ,Rare Diseases ,0302 clinical medicine ,Adrenal Cortex Hormones ,Recurrence ,medicine ,Humans ,Parotid Gland ,Histiocyte ,Rosai–Dorfman disease ,Skin ,business.industry ,Sinus Histiocytosis with Massive Lymphadenopathy ,medicine.disease ,Dermatology ,Parotid gland ,Emperipolesis ,Histiocytosis ,Treatment Outcome ,medicine.anatomical_structure ,Positron-Emission Tomography ,030220 oncology & carcinogenesis ,Etiology ,Lymph Node Excision ,Surgery ,Histiocytosis, Sinus ,business ,Follow-Up Studies - Abstract
Rosai-Dorfman disease (RDD), also known as sinus histiocytosis with massive lymphadenopathy, is a rare and benign proliferative disease that affects histiocytes. Its etiology remains unclear. Rosai-Dorfman disease primarily affects lymph nodes with many extranodal manifestations present, including cutaneous, pulmonary, ophthalmic, and gastrointestinal. Diagnosis is mainly histologic with the presence of Rosai-Dorfman cells, which demonstrate emperipolesis. We report a case of a 30-year-old man who presented with a facial cutaneous mass and was diagnosed with RDD; he underwent surgical excision. The patient experienced recurrent lesions on the surgical scar and parotid gland as well as the lower back. Treatment consisted of systemic steroids and surgical excision.
- Published
- 2019
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