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Your search keyword '"Michalski, Christoph W"' showing total 10 results
Start Over Author "Michalski, Christoph W" Journal annals of surgery
10 results on '"Michalski, Christoph W"'

2. Noninvasive Discrimination of Low and High-risk Pancreatic Intraductal Papillary Mucinous Neoplasms

Author

Roth, Susanne, primary, Bose, Promita, additional, Alhamdani, Mohamed S. S., additional, Mustafa, Shakhawan A., additional, Tjaden, Christine, additional, Zamzow, Katharina, additional, Hinz, Ulf, additional, Michalski, Christoph W., additional, Neoptolemos, John P., additional, Hoheisel, Jörg D., additional, Büchler, Markus W., additional, and Hackert, Thilo, additional

Published
2020
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3. Pylorus Resection Does Not Reduce Delayed Gastric Emptying After Partial Pancreatoduodenectomy

Author

Hackert, Thilo, primary, Probst, Pascal, additional, Knebel, Phillip, additional, Doerr-Harim, Colette, additional, Bruckner, Thomas, additional, Klaiber, Ulla, additional, Werner, Jens, additional, Schneider, Lutz, additional, Michalski, Christoph W., additional, Strobel, Oliver, additional, Ulrich, Alexis, additional, Diener, Markus K., additional, and Büchler, Markus W., additional

Published
2018
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4. Noninvasive Discrimination of Low and High-risk Pancreatic Intraductal Papillary Mucinous Neoplasms.

Author

Roth, Susanne, Bose, Promita, Alhamdani, Mohamed S. S., Mustafa, Shakhawan A., Tjaden, Christine, Zamzow, Katharina, Hinz, Ulf, Michalski, Christoph W., Neoptolemos, John P., Hoheisel, Jörg D., Büchler, Markus W., and Hackert, Thilo

Abstract

Objective: To propose a noninvasive diagnostic approach, which allows reliable distinction between low- and high-risk pancreatic intraductal papillary mucinous neoplasms (IPMNs). Background: IPMNs are identifiable precursor lesions of pancreatic cancer, of which surgical resection is warranted prior to the development of invasive carcinoma, but low-grade IPMNs should not be unnecessarily resected. However, diagnostic tools that preoperatively enable accurate risk stratification of IPMNs are missing. Methods: This single-center, retrospective cohort study included 56 patients who underwent surgical resection for IPMN including 18 low-risk (lowgrade) and 38 high-risk (high-grade/invasive carcinoma) IPMNs, from whom clinical features and serum samples were prospectively obtained. An antibody microarray platform was used to analyze the serum proteome. Based on serum markers and selected clinical characteristics support vector machine models were constructed to predict the risk of IPMN malignancy. Results: A serum protein signature discriminating low- and high-risk IPMN patients was identified. Combinations of established clinical features and the newly identified serum biomarkers correctly distinguished low- and high-risk IPMNs in 93% on 1000-fold cross-validation. Conclusions: This study highlights the synergistic predictive value of combining a novel serum protein signature with conventional clinical characteristics to risk-stratify IPMN patients. If these findings are supported by larger validation studies, they might enable more rational decision-making in clinical management of IPMN patients in conjunction with clinical guidelines. [ABSTRACT FROM AUTHOR]

Published
2021
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5. Locally Advanced Pancreatic Cancer

Author

Hackert, Thilo, primary, Sachsenmaier, Milena, additional, Hinz, Ulf, additional, Schneider, Lutz, additional, Michalski, Christoph W., additional, Springfeld, Christoph, additional, Strobel, Oliver, additional, Jäger, Dirk, additional, Ulrich, Alexis, additional, and Büchler, Markus W., additional

Published
2016
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6. Multicenter Double-Blinded Randomized Controlled Trial of Standard Abdominal Wound Edge Protection With Surgical Dressings Versus Coverage With a Sterile Circular Polyethylene Drape for Prevention of Surgical Site Infections

Author

Mihaljevic, André L., primary, Schirren, Rebekka, additional, Özer, Mine, additional, Ottl, Stephanie, additional, Grün, Sybille, additional, Michalski, Christoph W., additional, Erkan, Mert, additional, Jäger, Carsten, additional, Reiser-Erkan, Carolin, additional, Kehl, Victoria, additional, Schuster, Tibor, additional, Roder, Jürgen, additional, Clauer, Ulf, additional, Orlitsch, Carolin, additional, Hoffmann, Tomas F., additional, Lange, Reinhard, additional, Harzenetter, Thomas, additional, Steiner, Phillip, additional, Michalski, Milena, additional, Henkel, Karl, additional, Stadler, Josef, additional, Pistorius, Georg A., additional, Jahn, Anja, additional, Obermaier, Robert, additional, Unger, Robert, additional, Strunk, Roland, additional, Willeke, Frank, additional, Vogelsang, Holger, additional, Halve, Bert, additional, Dietl, Karl-Heinz, additional, Hilgenstock, Hendrik, additional, Meyer, Alexander, additional, Krämling, Hans-Jörg, additional, Wagner, Markus, additional, Schoenberg, Michael H., additional, Zeller, Florian, additional, Schmidt, Johannes, additional, Friess, Helmut, additional, and Kleeff, Jörg, additional

Published
2014
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7. Mucinous and Signet-Ring Cell Colorectal Cancers Differ from Classical Adenocarcinomas in Tumor Biology and Prognosis

Author

Nitsche, Ulrich, primary, Zimmermann, Anina, additional, Späth, Christoph, additional, Müller, Tara, additional, Maak, Matthias, additional, Schuster, Tibor, additional, Slotta-Huspenina, Julia, additional, Käser, Samuel A., additional, Michalski, Christoph W., additional, Janssen, Klaus-Peter, additional, Friess, Helmut, additional, Rosenberg, Robert, additional, and Bader, Franz G., additional

Published
2013
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