Search

Your search keyword '"Pohl C"' showing total 9 results
Start Over Author "Pohl C" Journal annals of the rheumatic diseases
9 results on '"Pohl C"'

2. Disparities in rheumatoid arthritis disease activity according to gross domestic product in 25 countries in the QUEST–RA database

Author

Sokka, T, Kautiainen, H, Pincus, T, Toloza, S, da Rocha Castelar Pinheiro, G, Lazovskis, J, Hetland, M L, Peets, T, Immonen, K, Maillefert, J F, Drosos, A A, Alten, R, Pohl, C, Rojkovich, B, Bresnihan, B, Minnock, P, Cazzato, M, Bombardieri, S, Rexhepi, S, Rexhepi, M, Andersone, D, Stropuviene, S, Huisman, M, Sierakowski, S, Karateev, D, Skakic, V, Naranjo, A, Baecklund, E, Henrohn, D, Gogus, F, Badsha, H, Mofti, A, Taylor, P, McClinton, C, and Yazici, Y

Published
2009
Full Text
View/download PDF

4. Patient's global assessment of disease activity and patient's assessment of general health for rheumatoid arthritis activity assessment: are they equivalent?

Author

Khan, Na, Spencer, Hj, Abda, Ea, Alten, R, Pohl, C, Ancuta, C, Cazzato, M, Géher, P, Gossec, L, Henrohn, D, Hetland, Ml, Inanc, N, Jacobs, Jw, Kerzberg, E, Majdan, M, Oyoo, O, Peredo Wende RA, Selim, Zi, Skopouli, Fn, Sulli, Alberto, Hørslev Petersen, K, Taylor, Pc, Sokka, T, and on behalf of QUEST RA group

Subjects
Adult, Male, medicine.medical_specialty, Databases, Factual, Health Status, Concordance, Immunology, Activity assessment, Arthritis, Severity of Illness Index, Article, General Biochemistry, Genetics and Molecular Biology, Arthritis, Rheumatoid, Disease activity, Rheumatology, Surveys and Questionnaires, Internal medicine, Severity of illness, medicine, Humans, Immunology and Allergy, Fatigue, Aged, business.industry, Middle Aged, medicine.disease, Arthralgia, Connective tissue disease, Rheumatoid arthritis, Physical therapy, Female, Self Report, General health, business
Abstract

OBJECTIVES: To assess (A) determinants of patient's global assessment of disease activity (PTGL) and patient's assessment of general health (GH) scores of rheumatoid arthritis (RA) patients; (B) whether they are equivalent as individual variables; and (C) whether they may be used interchangeably in calculating common RA activity assessment composite indices. METHODS: Data of 7023 patients from 30 countries in the Quantitative Standard Monitoring of Patients with RA (QUEST-RA) was analysed. PTGL and GH determinants were assessed by mixed-effects analyses of covariance models. PTGL and GH equivalence was determined by Bland-Altman 95% limits of agreement (BALOA) and Lin's coefficient of concordance (LCC). Concordance between PTGL and GH based Disease Activity Score 28 (DAS28), Clinical Disease Activity Index (CDAI) and Routine Assessment of Patient Index Data 3 (RAPID3) indices were calculated using LCC, and the level of agreement in classifying RA activity in four states (remission, low, moderate, high) using κ statistics. RESULTS: Significant differences in relative and absolute contribution of RA and non-RA related variables in PTGL and GH ratings were noted. LCC of 0.64 and BALOA of -4.41 to 4.54 showed that PTGL and GH are not equivalent. There was excellent concordance (LCC 0.95-0.99) for PTGL and GH based DAS28, CDAI and RAPID3 indices, and >80% absolute agreement (κ statistics 0.75-0.84) in RA activity state classification for all three indices. CONCLUSIONS: PTGL and GH ratings differ in their determinants. Although they are individually not equivalent, they may be used interchangeably for calculating composite indices for RA activity assessment.

Published
2012
Full Text
View/download PDF

5. FRI0142 High Prevalence of Depression in Patients with Rheumatoid Arthritis - Data from The Large Cross-Sectional Vadera II Study

Author

Englbrecht, M., primary, Alten, R., additional, Aringer, M., additional, Baerwald, C.G., additional, Burkhardt, H., additional, Eby, N., additional, Flacke, J.-P., additional, Fliedner, G., additional, Gauger, B., additional, Henkemeier, U., additional, Hofmann, M.W., additional, Kleinert, S., additional, Kneitz, C., additional, Krüger, K., additional, Lüthje, R., additional, Pohl, C., additional, Schett, G., additional, Schmalzing, M., additional, Tausche, A.-K., additional, Tony, H.P., additional, and Wendler, J., additional

Published
2016
Full Text
View/download PDF

7. Disparities in rheumatoid arthritis disease activity according to gross domestic product in 25 countries in the QUEST-RA database

Author

Sokka, T., Kautiainen, H., Pincus, T., Toloza, S., Castelar Pinheiro, G. da Rocha, Lazovskis, J., Hetland, M. L., Peets, T., Immonen, K., Maillefert, J. F., Drosos, A. A., Alten, R., Pohl, C., Rojkovich, B., Bresnihan, B., Minnock, P., Cazzato, M., Bombardieri, S., Rexhepi, S., Rexhepi, M., Andersone, D., Stropuviene, S., Huisman, M., Sierakowski, S., Karateev, D., Skakic, V., Naranjo, A., Baecklund, E., Henrohn, D., Gogus, F., Badsha, H., Mofti, A., Taylor, P., McClinton, C., Yazici, Y., Sokka, T., Kautiainen, H., Pincus, T., Toloza, S., Castelar Pinheiro, G. da Rocha, Lazovskis, J., Hetland, M. L., Peets, T., Immonen, K., Maillefert, J. F., Drosos, A. A., Alten, R., Pohl, C., Rojkovich, B., Bresnihan, B., Minnock, P., Cazzato, M., Bombardieri, S., Rexhepi, S., Rexhepi, M., Andersone, D., Stropuviene, S., Huisman, M., Sierakowski, S., Karateev, D., Skakic, V., Naranjo, A., Baecklund, E., Henrohn, D., Gogus, F., Badsha, H., Mofti, A., Taylor, P., McClinton, C., and Yazici, Y.

Abstract

Objective: To analyse associations between the clinical status of patients with rheumatoid arthritis ( RA) and the gross domestic product (GDP) of their resident country. Methods: The Quantitative Standard Monitoring of Patients with Rheumatoid Arthritis (QUEST-RA) cohort includes clinical and questionnaire data from 6004 patients who were seen in usual care at 70 rheumatology clinics in 25 countries as of April 2008, including 18 European countries. Demographic variables, clinical characteristics, RA disease activity measures, including the disease activity score in 28 joints (DAS28), and treatment-related variables were analysed according to GDP per capita, including 14 high GDP countries with GDP per capita greater than US$ 24 000 and 11 low GDP countries with GDP per capita less than US$ 11 000. Results: Disease activity DAS28 ranged between 3.1 and 6.0 among the 25 countries and was significantly associated with GDP (r = -0.78, 95% CI -0.56 to -0.90, r(2) = 61%). Disease activity levels differed substantially between high GDP and low GDP countries at much greater levels than according to whether patients were currently taking or not taking methotrexate, prednisone and/or biological agents. Conclusions: The clinical status of patients with RA was correlated significantly with GDP among 25 mostly European countries according to all disease measures, associated only modestly with the current use of antirheumatic medications. The burden of arthritis appears substantially greater in low GDP than in high GDP countries. These findings may alert healthcare professionals and designers of health policy towards improving the clinical status of patients with RA in all countries.

Published
2009

9. Identifying core domains to assess flare in rheumatoid arthritis: an OMERACT international patient and provider combined Delphi consensus.

Author

Bartlett SJ, Hewlett S, Bingham CO 3rd, Woodworth TG, Alten R, Pohl C, Choy EH, Sanderson T, Boonen A, Bykerk V, Leong AL, Strand V, Furst DE, and Christensen R

Subjects
Arthritis, Rheumatoid physiopathology, Disability Evaluation, Disease Progression, Female, Health Status, Humans, International Cooperation, Joints pathology, Joints physiopathology, Male, Middle Aged, Severity of Illness Index, Arthritis, Rheumatoid diagnosis, Consensus, Delphi Technique, Diagnostic Self Evaluation, Health Personnel, Patient Acuity
Abstract

Objective: For rheumatoid arthritis (RA), there is no consensus on how to define and assess flare. Variability in flare definitions impairs understanding of findings across studies and limits ability to pool results. The OMERACT RA Flare Group sought to identify domains to define RA flares from patient and healthcare professional (HCP) perspectives., Methods: Flare was described as a worsening of disease activity of sufficient intensity and duration to consider a change in therapy. International patients and HCPs participated in separate and combined rounds of Delphi exercises to rate candidate flare domains previously generated in patient focus groups. Core domains were defined as those with ≥70% ratings of being 'essential' according to the third/final Delphi exercise., Results: The final Delphi included 125 RA patients from 10 countries and 108 HCPs from 23 countries who rated 14 domains. Patients had a mean (±SD) age of 56±12 years and disease duration of 18±12 years. HCPs included physicians from clinical practice/research and industry, allied health providers and researchers with 17±11 years experience. Core domains comprised: pain (93%), function (89%), swollen joints (84%), tender joints (81%), participation (81%), stiffness (79%), patient global assessment (76%) and self-management (75%). Fatigue (68%), which did not reach group consensus, will receive additional consideration., Conclusions: As part of the process to develop a measure for RA flare, patients and HCPs agreed on eight core domains. Next steps include identifying items to assess domains and conducting studies to validate and refine a new measure.

Published
2012
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results