1. Economic evaluation of endoscopic versus open vein harvest for coronary artery bypass grafting.
- Author
-
Oddershede L, Andreasen JJ, Brocki BC, and Ehlers L
- Subjects
- Aged, Coronary Artery Bypass methods, Cost-Benefit Analysis, Endoscopy, Female, Humans, Male, Middle Aged, Randomized Controlled Trials as Topic, Saphenous Vein transplantation, Tissue and Organ Harvesting adverse effects, Tissue and Organ Harvesting methods, Coronary Artery Bypass economics, Saphenous Vein surgery, Tissue and Organ Harvesting economics
- Abstract
Background: A short saphenous vein segment is commonly used as a conduit for coronary artery bypass grafting, and clinicians must decide whether to obtain it by performing open (OVH) or endoscopic vein harvest (EVH). We conducted a health economic evaluation, using data on resource usage collected alongside a randomized controlled trial, to investigate whether EVH is cost-effective compared with OVH., Methods: Analyses were performed in accordance with international guidelines for health economic evaluations. We constructed 3 cost-levels as the current literature is inconclusive as to which resource consumptions differ significantly between harvesting methods. Outcomes were measured as purulent infections avoided in the cost-effectiveness analysis and for the cost-utility analysis we estimated quality-adjusted life-years gained. Results were presented as incremental cost-effectiveness ratios: ie, the extra cost of obtaining one extra quality-adjusted life-year and the extra cost of avoiding one purulent infection. To handle uncertainties, we performed bias corrected bootstrap analyses on 5,000 resamples and constructed cost-effectiveness acceptability curves., Results: The incremental cost-effectiveness ratio was $79,391/quality-adjusted life-year and $1,970/purulent infection avoided when costs and outcomes within 35 days postoperatively were compared. Within 35 days postoperatively, EVH was less than 1% cost-effective at a willingness-to-pay threshold of $50,000/quality-adjusted life-year., Conclusions: The EVH was not cost-effective within 35 days postoperatively. Future studies should investigate long-term cost effectiveness., (Copyright © 2012 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.)
- Published
- 2012
- Full Text
- View/download PDF