1. Percutaneous Angioplasty of Long Tibial Occlusions in Critical Limb Ischemia
- Author
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Réda Hassen-Khodja, Aurélien Mousnier, Serge Declemy, Nirvana Sadaghianloo, Elixène Jean-Baptiste, and Sophie Brizzi
- Subjects
Male ,medicine.medical_specialty ,Time Factors ,Critical Illness ,medicine.medical_treatment ,Technical success ,Target vessel revascularization ,Constriction, Pathologic ,Kaplan-Meier Estimate ,Revascularization ,Amputation, Surgical ,Percutaneous angioplasty ,Peripheral Arterial Disease ,Ischemia ,Risk Factors ,Humans ,Medicine ,Prospective Studies ,Vascular Patency ,Aged ,Proportional Hazards Models ,Aged, 80 and over ,Wound Healing ,business.industry ,General Medicine ,Critical limb ischemia ,Middle Aged ,Limb Salvage ,Surgery ,Tibial Arteries ,Logistic Models ,Treatment Outcome ,medicine.anatomical_structure ,Lower Extremity ,Multivariate Analysis ,Female ,medicine.symptom ,Cardiology and Cardiovascular Medicine ,business ,Angioplasty, Balloon ,Cohort study ,Artery ,Major amputation - Abstract
Background The aim of this study was to assess the midterm results of percutaneous angioplasty in patients with critical limb ischemia (CLI) and long tibial occlusions. Methods Between January and September 2011, 34 consecutive patients with patent femoropopliteal artery and 49 segmental tibial occlusions >8 cm were included in our prospective, single-center cohort study. Clinical success (defined as wound healing and survival without major amputation), patency, and freedom from target vessel revascularization (TVR) were examined. Results The median age of the patients was 75 (53–89) years, 74% were diabetic, and 89% of the limbs studied were Rutherford 5 and 6. Median follow-up was 12.5 (1–15) months. The 1-year clinical success rate was 65%, higher among patients with technical success (76% vs. 25%, P = 0.01) and patients with 2 or 3 patent tibial arteries after the procedure (90% vs. 41% in patients with only 1 patent artery, P = 0.003). At 1 year, primary and secondary patency rates were 13% and 32%, respectively (24% and 58% without technical failures). The 1-year freedom-from-TVR rate was 34%. Conclusions Despite high technical failure rates and the need for repeat procedures, percutaneous angioplasty of long tibial occlusions enhances wound healing, especially when integrated into a maximal revascularization approach.
- Published
- 2013
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