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Your search keyword '"Naoko Yoshizawa-Sugata"' showing total 2 results
Start Over Author "Naoko Yoshizawa-Sugata" Journal annual review of biochemistry
2 results on '"Naoko Yoshizawa-Sugata"'

1. Eukaryotic chromosome DNA replication: where, when, and how?

Author

Masai, Hisao, Matsumoto, Seiji, Zhiying You, Naoko Yoshizawa-Sugata, and Masako Oda

Subjects
DNA replication -- Analysis, Eukaryotes -- Physiological aspects, Eukaryotes -- Genetic aspects, Genetic regulation -- Analysis, Biological sciences
Published
2010

2. Eukaryotic Chromosome DNA Replication: Where, When, and How?

Author

Seiji Matsumoto, Naoko Yoshizawa-Sugata, Zhiying You, Hisao Masai, and Masako Oda

Subjects
DNA Replication, Genetics, Semiconservative replication, DNA replication, Replication Origin, Eukaryotic DNA replication, Computational biology, Biology, Origin of replication, Pre-replication complex, Biochemistry, Chromosomes, S Phase, Licensing factor, Control of chromosome duplication, Animals, Humans, Origin recognition complex
Abstract

DNA replication is central to cell proliferation. Studies in the past six decades since the proposal of a semiconservative mode of DNA replication have confirmed the high degree of conservation of the basic machinery of DNA replication from prokaryotes to eukaryotes. However, the need for replication of a substantially longer segment of DNA in coordination with various internal and external signals in eukaryotic cells has led to more complex and versatile regulatory strategies. The replication program in higher eukaryotes is under a dynamic and plastic regulation within a single cell, or within the cell population, or during development. We review here various regulatory mechanisms that control the replication program in eukaryotes and discuss future directions in this dynamic field.

Published
2010
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