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Your search keyword '"Methicillin metabolism"' showing total 3 results
Start Over Descriptor "Methicillin metabolism" Journal antibiotiki
3 results on '"Methicillin metabolism"'

1. [Body pharmacokinetics of methicillin, oxacillin and cephaloridine in puerperal mastitis].

Author

Kulakov VI, Zak IR, Kulikova NN, and Smekuna FA

Subjects
Adult, Female, Humans, Kinetics, Milk, Human metabolism, Pregnancy, Time Factors, Cephaloridine metabolism, Mastitis metabolism, Methicillin metabolism, Oxacillin metabolism, Puerperal Infection metabolism
Abstract

Mechanisms of absorption, distribution and excretion of methicillin, oxacillin and cephaloridin were studied in 46 women with postnatal mastitis (serous and infiltrative forms). The results obtained allow one to document different clinical efficiency of antibiotics in treatment of patients with postnatal mastitis. Poor efficiency of cephaloridin in therapy of mastitis was shown.

Published
1981

2. [Phamacokinetics of methicillin, oxacillin and cephalosporin in the body of puerperae].

Author

Kulakov VI, Kulikova NN, Minasova GS, and Smekuna FA

Subjects
Absorption, Adult, Biopharmaceutics, Dose-Response Relationship, Drug, Female, Humans, Kinetics, Pregnancy, Time Factors, Cephalosporins metabolism, Methicillin metabolism, Oxacillin metabolism, Puerperal Infection metabolism
Abstract

Features of absorption, distribution and excretion of methicillin, oxacillin and cephaloridine in 58 puerpera were studied. No complications were observed in the postnatal period of the puerpera. The results of the study of the antibiotic pharmacokinetics provided elaboration of the optimal regimen for the use of methicillin, oxacillin and cephaloridine in puerpera, i. e. I g intramuscularly every 6 hours.

Published
1978

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