1. Epidemiological and Clinical Characteristics of International Travelers with Enteric Fever and Antibiotic Resistance Profiles of Their Isolates: a GeoSentinel Analysis
- Author
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Bradley A. Connor, Prativa Pandey, Martin P. Grobusch, Paul Kelly, Eli Schwartz, Frank P. Mockenhaupt, Eric Caumes, Silvia Odolini, Ralph Huits, Perry J.J. van Genderen, Patricia Schlagenhauf, Mogens Jensenius, Davidson H. Hamer, Anne E. McCarthy, Yukihiro Yoshimura, Daniel L. Bourque, Kristina M. Angelo, Karin Leder, Hilmir Asgeirsson, Katherine Plewes, Michael Libman, Stefan H.F. Hagmann, Daniel T. Leung, Adrián Sánchez-Montalvá, Gilles Eperon, Infectious diseases, AII - Infectious diseases, APH - Aging & Later Life, APH - Global Health, Internal Medicine, Medical Microbiology & Infectious Diseases, University of Zurich, and Hagmann, Stefan H F
- Subjects
Serotype ,medicine.medical_specialty ,Asia ,Adolescent ,030231 tropical medicine ,India ,610 Medicine & health ,Enteric fever ,Drug resistance ,Antimicrobial resistance ,Typhoid fever ,Epidemiology and Surveillance ,03 medical and health sciences ,0302 clinical medicine ,Antibiotic resistance ,Internal medicine ,medicine ,Typhoid ,2736 Pharmacology (medical) ,Humans ,Pharmacology (medical) ,030212 general & internal medicine ,Typhoid Fever ,Child ,Pharmacology ,Antiinfective agent ,Travel ,business.industry ,Paratyphoid fever ,Drug Resistance, Microbial ,10060 Epidemiology, Biostatistics and Prevention Institute (EBPI) ,2725 Infectious Diseases ,Salmonella typhi ,medicine.disease ,Trimethoprim ,Anti-Bacterial Agents ,Paratyphoid ,3004 Pharmacology ,Infectious Diseases ,Salmonella paratyphi A ,Coinfection ,business ,Travel-Related Illness ,human activities ,medicine.drug - Abstract
Enteric fever, caused by Salmonella enterica serovar Typhi (S. Typhi) and S. enterica serovar Paratyphi (S. Paratyphi), is a common travel-related illness. Limited data are available on the antimicrobial resistance (AMR) patterns of these serovars among travelers. Records of travelers with a culture-confirmed diagnosis seen during or after travel from January 2007 to December 2018 were obtained from GeoSentinel. Traveler demographics and antimicrobial susceptibility data were analyzed. Isolates were classified as nonsusceptible if intermediate or resistant or as susceptible in accordance with the participating site’s national guidelines. A total of 889 travelers (S. Typhi infections, n = 474; S. Paratyphi infections, n = 414; coinfection, n = 1) were included; 114 (13%) were children of
- Published
- 2020