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Your search keyword '"R. A. Nazeer"' showing total 2 results
Start Over Author "R. A. Nazeer" Journal applied biochemistry and biotechnology
2 results on '"R. A. Nazeer"'

1. Anti-inflammatory Properties of Bioactive Peptide Derived from Gastropod Influenced by Enzymatic Hydrolysis

Author

R. A. Nazeer, Ila Joshi, and Sekar Sudhakar

Subjects
Lipopolysaccharides, 0301 basic medicine, Spectrometry, Mass, Electrospray Ionization, Arginine, Cell Survival, Protein Hydrolysates, Gastropoda, Interleukin-1beta, Anti-Inflammatory Agents, Bioengineering, Peptide, Chemical Fractionation, Nitric Oxide, Applied Microbiology and Biotechnology, Biochemistry, Hydrolysate, Cell Line, 03 medical and health sciences, 0404 agricultural biotechnology, Enzymatic hydrolysis, Aspartic acid, medicine, Animals, Humans, Trypsin, Amino Acid Sequence, Amino Acids, Molecular Biology, chemistry.chemical_classification, Tumor Necrosis Factor-alpha, Hydrolysis, 04 agricultural and veterinary sciences, General Medicine, 040401 food science, Amino acid, Molecular Weight, 030104 developmental biology, chemistry, Proteolysis, Leucine, Peptides, Biotechnology, medicine.drug
Abstract

The visceral mass of the gastropod, Harpa ventricosa was hydrolysed using trypsin, alcalase and pepsin for 12 h to produce protein hydrolysates. Subsequently, the active hydrolysate was observed in the 3rd hour of tryptic hydrolysate (29.17 ± 0.62 and 34.85 ± 0.55 %) using human red blood cell (HRBC) membrane stabilization and albumin denaturation (AD) assays. The active hydrolysate was fractionated by membrane filtration unit, where

Published
2016
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2. Anticoagulant, Antiherpetic and Antibacterial Activities of Sulphated Polysaccharide from Indian Medicinal Plant Tridax procumbens L. (Asteraceae)

Author

Shabeena Yousuf Naqash and R. A. Nazeer

Subjects
Chemistry, Pharmaceutical, Tridax procumbens, Hemorrhage, Bioengineering, Herpesvirus 1, Human, Asteraceae, Biology, Antiviral Agents, Applied Microbiology and Biotechnology, Biochemistry, Microbiology, Inhibitory Concentration 50, Polysaccharides, Chlorocebus aethiops, medicine, Animals, Vero Cells, Molecular Biology, IC50, Vibrio alginolyticus, Plants, Medicinal, Heparin, Plant Extracts, Vibrio harveyi, Chondroitin Sulfates, Anticoagulants, Herpes Simplex, General Medicine, biology.organism_classification, Anti-Bacterial Agents, Vibrio Infections, Vero cell, Partial Thromboplastin Time, Antibacterial activity, Phytotherapy, Biotechnology, medicine.drug
Abstract

The sulphated polysaccharide from the widespread Tridax procumbens plant was studied for the anticoagulant, antiherpetic and antibacterial activity. The anticoagulant activity was determined by the activated partial thromboplastin time assay. The sulphated polysaccharide from T. procumbens represented potent anticoagulant reaching the efficacy to heparin and chondroitin sulphate. Moreover, the sulphated polysaccharide extracted from T. procumbens was found non-toxic on Vero cell lines up to the concentration of 200 μg/ml. Sulphated polysaccharide exhibited detectable antiviral effect towards HSV-1 with IC(50) value 100-150 μg/ml. Furthermore, sulphated polysaccharide from T. procumbens was highly inhibitory against the bacterial strains Vibrio alginolyticus and Vibrio harveyi isolated from oil sardine.

Published
2011
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