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In this paper, an optimal control model for the transmission dynamics of COVID-19 is investigated. We established important model properties like nonnegativity and boundedness of solutions, and also the region of invariance. Further, an expression for the basic reproduction number is computed and its sensitivity w.r.t model parameters is carried out to identify the most sensitive parameter. Based on sensitivity analysis, optimal control strategies were presented to reduce the disease burden and related costs. It is demonstrated that optimal control does exist and is unique. The characterization of optimal trajectories is analytically studied via Pontryagin's Minimum Principle. Moreover, various simulations were performed to support analytical results. The simulation results showed that the proposed controls significantly influence the disease burden compared to the absence of control cases. Further, it reveals that the applied control strategies are effective throughout the intervention period in reducing COVID-19 diseases in the community. Besides, the simulation results of the optimal control suggested that concurrently applying all controlling strategies outperform in mitigating the spread of COVID-19 compared to any other preventive measures. [ABSTRACT FROM AUTHOR]

The world is grappled with an unprecedented challenges due to Corona virus. We are all battling this epidemic together, but we have not been able to defeat this epidemic yet. A new variant of this virus, named 'Omicron' is spreading these days. The fractional differential equations are providing us with better tools to study the mathematical model with memory effects. In this paper, we will consider an extended SER mathematical model with quarantined and vaccinated compartment to speculate the Omicron variant. This extended Susceptible Exposed Infected Recovered SER model involves equations that associate with the group of individuals those are susceptible (S), exposed (E): this class includes the individuals who are infected but not yet infectious, infectious (W): this class includes the individuals who are infected but not yet Quarantined, quarantined (Q): this class includes those group of people who are infectious, confirmed and quarantined, recovered (R) this class includes the group of individuals who have recovered, and vaccinated (V): this class includes the group of individuals who have been vaccinated. The non-negativity and of the extended SER model is analysed, the equilibrium points and the basic reproduction number are also calculated. The proposed model is then extended to the mathematical model using AB derivative operator. Proof for the existence and the uniqueness for the solution of fractional mathematical model in sense of AB fractional derivative is detailed and a numerical method is detailed to obtain the numerical solutions. Further we have discussed the efficiency of the vaccine against the Omicron variant via graphical representation. [ABSTRACT FROM AUTHOR]

The 2019 new coronavirus illness (COVID-19) is an international public health emergency. Our social and healthcare systems are under a great deal of strain as a result of the daily increase in infection rates and fatalities. Doctors typically perform a chest Xray to identify the diseased areas of the lungs since pneumonia is a common type of infection that spreads in the lungs. In this paper, we propose a Convolution Neural Network via the li regularization model to detect COVID-19 patients using chest X-Ray images. Due to the lack of the COVID-19 benchmark dataset, we use deep learning techniques to identify the best pre-trained CNN model for this job by comparing 15 models. The suggested algorithm was tested on 1316 photos (116 COVID-19 cases, 328 healthy controls, and 872 pneumonia cases), with 66% for training, 17% for validation, and 17% for testing. The classification accuracy, loss, valueaccuracy, and value-loss values obtained by the suggested technique are 0.9912, 0.0187, 0.1119, and 0.9506 respectively. Additionally, the model effectively decreases training loss while boosting accuracy. The results show that proposed procedures are more effective than existing ones at identifying COVID-19 cases from chest X-ray pictures. [ABSTRACT FROM AUTHOR]

As COVID-19 is an emerging pandemic, analysing its evolution is necessary to understand it in order to find appropriate answers. In this paper, we aim to observe and analyse it at the Chadian-Senegalese level. Thus, we collect public data in order to present via curves, histograms and tables the main characteristics of this pandemic. In this way, we implement a python program to construct these. We focus only on extracting long-term data without predictive models. We observed that there are mainly two waves (outbreak) per year with stable or even decreasing infection and death rates. We also identified moments of growth and relaxation of the disease. These results can be used to identify times when treatment or prevention should be intensified. [ABSTRACT FROM AUTHOR]

The paper's main aim is to investigate the 2019 coronavirus disease in Ethiopia using a fractional-order mathematical model. It would also focus on the importance of fractional-order derivatives that may help us in modelling the system and understanding the effect of model parameters and fractional derivative orders on the approximate solutions of our model. A SELAIQHCR model is constructed using nonlinear differential equations in the Atangana–Baleanu non-integer operator in the Caputo sense. After that, the Chebyshev fourth kind spectral collocation method is used to change a fractional system to an algebraic system. Newton iterative technique is used to solve the converted system. The next-generation matrix technique is used to obtain the effective reproduction number. The COVID-19-free equilibrium point and endemic equilibrium point, solution positivity and boundedness, and their stability are all carefully done. The sensitivity of the effective reproduction value with respect to the key model parameters is discussed. The beginning values provided for our system were obtained using reports from the Ethiopian Public Health Institute from 29 February 2021 to 7 June 2021. The fundamental reproduction number is obtained with R 0 = 1.4331. The model's numerical solutions are represented graphically. [ABSTRACT FROM AUTHOR]