1. Continuous production of isopropanol and butanol using Clostridium beijerinckii DSM 6423.
- Author
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Survase, Shrikant A., Jurgens, German, Van Heiningen, Adriaan, and Granström, Tom
- Subjects
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CLOSTRIDIUM biotechnology , *ISOPROPYL alcohol , *BUTANOL , *WOOD-pulp , *SOLVENTS , *BIOTECHNOLOGY - Abstract
Clostridium beijerinckii DSM 6423 was studied using different continuous production methods to give maximum and stable production of isopropanol and n-butanol. In a single-stage continuous culture, when wood pulp was added as a cell holding material, we could increase the solvent productivity from 0.47 to 5.52 g L h with the yield of 54% from glucose. The overall solvent concentration of 7.51 g L (39.4% isopropanol and 60.6% n-butanol) with the maximum solvent productivity of 0.84 g L h was obtained with two-stage continuous culture. We were able to run the process for more than 48 overall retention times without losing the ability to produce solvents. [ABSTRACT FROM AUTHOR]
- Published
- 2011
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