1. A Deep Learning-Based Diagnosis System for COVID-19 Detection and Pneumonia Screening Using CT Imaging
- Author
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Ramzi Mahmoudi, Narjes Benameur, Rania Mabrouk, Mazin Abed Mohammed, Begonya Garcia-Zapirain, and Mohamed Hedi Bedoui
- Subjects
SARS-CoV-2 ,CT scans ,deep learning ,lung segmentation ,infection segmentation ,classification ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
Background: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a global threat impacting the lives of millions of people worldwide. Automated detection of lung infections from Computed Tomography scans represents an excellent alternative; however, segmenting infected regions from CT slices encounters many challenges. Objective: Developing a diagnosis system based on deep learning techniques to detect and quantify COVID-19 infection and pneumonia screening using CT imaging. Method: Contrast Limited Adaptive Histogram Equalization pre-processing method was used to remove the noise and intensity in homogeneity. Black slices were also removed to crop only the region of interest containing the lungs. A U-net architecture, based on CNN encoder and CNN decoder approaches, is then introduced for a fast and precise image segmentation to obtain the lung and infection segmentation models. For better estimation of skill on unseen data, a fourfold cross-validation as a resampling procedure has been used. A three-layered CNN architecture, with additional fully connected layers followed by a Softmax layer, was used for classification. Lung and infection volumes have been reconstructed to allow volume ratio computing and obtain infection rate. Results: Starting with the 20 CT scan cases, data has been divided into 70% for the training dataset and 30% for the validation dataset. Experimental results demonstrated that the proposed system achieves a dice score of 0.98 and 0.91 for the lung and infection segmentation tasks, respectively, and an accuracy of 0.98 for the classification task. Conclusions: The proposed workflow aimed at obtaining good performances for the different system’s components, and at the same time, dealing with reduced datasets used for training.
- Published
- 2022
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