1. Self-assembly of chitosan and cellulose chains into a 3D porous polysaccharide alloy films: Co-dissolving, structure and biological properties.
- Author
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Zhang, Ruihong, Xie, Jinyu, Yang, Binbin, Fu, Feiya, Tang, Haiyue, Zhang, Jingjing, Zhao, Yanteng, Zhang, Yanyan, Liu, Lin, Zhu, Yaofeng, Liu, Xiangdong, Zhou, Jinping, and Yao, Juming
- Subjects
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MORPHOLOGY , *POLYSACCHARIDES , *CELLULOSE , *POLYMER films , *3-D films , *ALLOYS - Abstract
Blending of plant-based cellulose and marine-derived chitosan in micro-level has potential to make fascinating materials. However, this task is frequently hindered by the poor solubility of the polysaccharides. Here, using a green alkali/urea solvent media together with a well-designed dissolving strategy, original cellulose pulp and chitosan power were dispersed into a homogeneous solution. Driven by the intermolecular hydrogen-bond interaction, cellulose and chitosan chains were facially self-assembled into a unique 3D alloy structure. Owing to the rich interface interactions, the tensile strength and breaking elongation of the alloy film increased by 69% and 260%, respectively, when compared to a pure chitosan film. Besides, the 3D alloy films with a pore diameter of 920–1435 nm exhibited an extremely high cell viability which was higher than 95%. Additionally, accelerated wound healing rate of 95.6% reached in the presence of the alloy film after two weeks using a full-thickness wound in a rat model. Unlabelled Image • Chitosan and cellulose were co-dissolved into one green alkali/urea solvent. • Polysaccharide chains were self-assembled into 3D porous alloy films. • Abundant interface interactions led to excellent physicochemical properties. • Biocompatibility and bioactivity of the alloy result in good wound healing. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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