1. Tolerance of bivalve mollusc hemocytes to variable oxygen availability: a mitochondrial origin?
- Author
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Christophe Lambert, Ludovic Donaghy, Hélène Hégaret, Nelly Le Goïc, Sébastien Artigaud, Rossana Sussarellu, Philippe Soudant, Laboratoire des Sciences de l'Environnement Marin (LEMAR) (LEMAR), Institut de Recherche pour le Développement (IRD)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Université de Brest (UBO)-Institut Universitaire Européen de la Mer (IUEM), and Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Brest (UBO)-Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Brest (UBO)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)
- Subjects
Oyster ,[SDE.MCG]Environmental Sciences/Global Changes ,chemistry.chemical_element ,Hemocyte ,Aquatic Science ,Mitochondrion ,Oxygen ,03 medical and health sciences ,[SDV.EE.ECO]Life Sciences [q-bio]/Ecology, environment/Ecosystems ,0302 clinical medicine ,biology.animal ,Flow cytometry ,Hypoxia ,Inner mitochondrial membrane ,030304 developmental biology ,chemistry.chemical_classification ,0303 health sciences ,Reactive oxygen species ,[SDV.BA.MVSA]Life Sciences [q-bio]/Animal biology/Veterinary medicine and animal Health ,biology ,Ecology ,Hypoxia (environmental) ,Pacific oyster ,biology.organism_classification ,Mitochondria ,Cell biology ,[SDV.BA.ZI]Life Sciences [q-bio]/Animal biology/Invertebrate Zoology ,chemistry ,[SDV.SA.STP]Life Sciences [q-bio]/Agricultural sciences/Sciences and technics of fishery ,Crassostrea ,[SDE.BE]Environmental Sciences/Biodiversity and Ecology ,030217 neurology & neurosurgery ,[SDV.EE.IEO]Life Sciences [q-bio]/Ecology, environment/Symbiosis - Abstract
International audience; Bivalve molluscs survive lack of oxygen and may present cellular characteristics allowing tolerance tooxygen deprivation. The objective of the present work was to determine in vitro responses of circulating cells (i.e.,hemocytes) of Pacific oyster, Crassostrea gigas, to oxygen deprivation by analysis of mitochondrial membrane potential(ΔΨm) and reactive oxygen species (ROS) production. Hemocytes submitted to oxygen deprivation showed areduced ROS production and an increased ΔΨm. Confrontation of present results with recently reported findings allowsus to hypothesize the existence of an alternative mitochondrial reductase, and the involvement of mitochondrial potassiumchannel in maintenance of ΔΨm. Tolerance of bivalve hemocytes to variable oxygen availability appears, at leastpartially, related to mitochondrial specificities.
- Published
- 2013
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