1. Encephalopathy in children: an approach to assessment and management
- Author
-
Santosh R. Mordekar, Emily Davies, and Daniel J. A. Connolly
- Subjects
medicine.medical_specialty ,Pediatrics ,media_common.quotation_subject ,Encephalopathy ,MEDLINE ,Hypoxia ischemia ,Brain diagnosis ,Autoimmune Diseases ,Diagnosis, Differential ,Presentation ,Central Nervous System Infections ,X ray computed ,Medicine ,Humans ,Intensive care medicine ,Child ,media_common ,Brain Diseases ,business.industry ,medicine.disease ,Magnetic Resonance Imaging ,Brain Injuries ,Pediatrics, Perinatology and Child Health ,Hypoxia-Ischemia, Brain ,Differential diagnosis ,business ,Tomography, X-Ray Computed - Abstract
Childhood encephalopathy is an uncommon but significant paediatric presentation and is associated with significant mortality and long-term morbidity in survivors. By definition it is a somewhat non-specific presentation with a wide differential diagnosis and long list of possible investigations. Choice of investigation, including neuroimaging modality, can be a daunting prospect for the clinician faced with the encephalopathic child and it is important to select appropriately for a high diagnostic yield. Initial management centres on good emergency care irrespective of cause. More specific therapies however vary enormously, and appropriate treatment is important and influences outcome. Evidence exists for mana©gement of many of the individual conditions causing encephalopathy. This review aims to outline a clinical approach to selecting investigations to identify a specific cause and provides an overview of the treatment for the commoner causes of encephalopathy that a general paediatrician may reasonably expect to be faced with.
- Published
- 2011