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2 results on '"Chaim Zinman"'

1. Hip fractures in the elderly in Israel—Possible impact of preventable conditions

Author

Batia Raz, Sophia Ish-Shalom, Chaim Zinman, Sophia Rimbrot, Valentina Raichlin, and Elena Segal

Subjects
Male, Aging, medicine.medical_specialty, Deoxypyridinoline, Health (social science), Poison control, vitamin D deficiency, Bone resorption, Bone remodeling, Diabetes Complications, chemistry.chemical_compound, Sex Factors, Risk Factors, Internal medicine, Vitamin D and neurology, Humans, Medicine, Israel, Aged, Aged, 80 and over, Hip fracture, Hip Fractures, business.industry, Age Factors, Vitamin D Deficiency, medicine.disease, Surgery, Logistic Models, chemistry, Case-Control Studies, Female, Seasons, Geriatrics and Gerontology, business, Gerontology, Body mass index
Abstract

In the present study we evaluated the possible contribution of different factors to the occurrence of hip fractures in Israel. We assessed medical history, physical activity, body mass index, smoking status, bone turnover markers and calcium regulating hormones levels of 142 consecutive elderly hip fracture patients (HFP), and compared them to 96 community dwelling elderly people without a history of hip fracture. Age and female gender were the strongest predictors of hip fracture, p

Published
2009
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2. Low patient compliance--a major negative factor in achieving vitamin D adequacy in elderly hip fracture patients supplemented with 800IU of vitamin D3 daily

Author

Sophia Ish-Shalom, Chaim Zinman, Elena Segal, and Batia Raz

Subjects
Vitamin, Male, Aging, medicine.medical_specialty, Health (social science), Time Factors, chemistry.chemical_compound, Internal medicine, medicine, Vitamin D and neurology, Humans, Vitamin D, Patient compliance, Aged, Cholecalciferol, Aged, 80 and over, Hip fracture, business.industry, Hip Fractures, Middle Aged, medicine.disease, Surgery, chemistry, Blood chemistry, Parathyroid Hormone, Patient Compliance, Female, Geriatrics and Gerontology, business, Gerontology, Hospital stay
Abstract

Achievement of adequate vitamin D3 level is crucial for the treatment of hip fracture patients. Currently used vitamin D3 supplementation in Israel ranges between 200 and 800IU/day. The study objectives were to evaluate the effects of 800IU/day vitamin D3 and 1.200mg of calcium carbonate supplementation to achieve adequate vitamin D3 level of 30ng/ml in elderly hip fracture patients. One hundred and twenty-two elderly patients after surgical hip fracture correction aged 73.0+/-9.5, who were enrolled in a post-surgical treatment program (PSTP). The patients received 800IU of vitamin D3 and 1.200mg of calcium carbonate daily. Serum 25(OH)D and plasma PTH levels were assessed during initial hospital stay and at quarterly follow-up visits for 2 years. At baseline, 120 patients (98.4%) had 25(OH)D serum level30ng/ml. Forty-two patients (34.4%) had 25(OH)D serum level10ng/ml and these were considered as vitamin D(3) deficient. After 3 months, 29 patients (23.8%) were fully adherent to the supplement, 32 were (26.2%) partially adherent. The dropout rate at 1 year was 55.7%. The major reason for the discontinuation of participation was non-compliance. We conclude that the majority of elderly hip fracture patients had inadequate 25(OH)D serum levels. Compliance with calcium and vitamin D3 supplements was extremely low. An adequate vitamin D status was not achieved with daily vitamin D3 supplementation of 800IU. Supplementation strategies using a periodic single high dose of vitamin D3 might be more appropriate and should be considered in these patients.

Published
2008

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