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The introduction of penicillin has caused a renewed interest in the treatment of early 1 and late 2 syphilis. In this paper an account is given of the course of early dementia paralytica in a man aged 31 who at no time was subjected to any other form of therapy. Treatment with penicillin appeared to produce a remission. Psychologic examinations made before and after treatment confirmed the clinical impression of remission and permitted a roughly quantitative estimate of the degree of improvement. Since serologic reversal is often minimal or absent when penicillin alone is used in the treatment of late syphilis, it is suggested that psychologic examinations, repeated at stated intervals, may provide an early indication for repetition of treatment. The clinical methods used in this study were the standard physical, neurologic and serologic tests and examination of the cerebrospinal fluid. The psychologic methods utilized were the Wechsler-Bellevue Adult Scale

It has been the experience of many observers that in cases of intra-spinal tumor the information given by injection of iodized poppy seed oil 40 per cent may be misleading and deceptive. This observation, coupled with recent reports of toxic effects following iodolography, has led to a wave of condemnation of the use of iodized oils in the subarachnoid space. In this paper I present 4 cases of tumor of the conus medullaris or cauda equina as illustrations of the belief that in the diagnosis of tumors of this region the advantages of the use of iodized poppy seed oil outweigh objections to it. DIFFERENTIAL DIAGNOSIS BETWEEN TUMORS OF THE CONUS MEDULLARIS AND CAUDA EQUINA While clinical methods for the differentiation of lesions of the conus from those of the cauda are frequently given, actual experience will soon demonstrate their uncertainty. Cushing and Ayer1pointed out that the diagnosis