Search

Your search keyword '"Osamu Udagawa"' showing total 1 results
Start Over Author "Osamu Udagawa" Journal archives of toxicology
1 results on '"Osamu Udagawa"'

1. SUMOylation regulates the number and size of promyelocytic leukemia-nuclear bodies (PML-NBs) and arsenic perturbs SUMO dynamics on PML by insolubilizing PML in THP-1 cells

Author

Seishiro Hirano and Osamu Udagawa

Subjects
Sulfonamides, Arsenites, THP-1 Cells, Health, Toxicology and Mutagenesis, Nuclear Proteins, Sumoylation, Esters, General Medicine, CHO Cells, Promyelocytic Leukemia Protein, Sulfides, Toxicology, Cricetulus, Pyrimidines, Solubility, Cricetinae, Small Ubiquitin-Related Modifier Proteins, Animals, Humans, Pyrazoles, Sulfonic Acids, Ubiquitins
Abstract

The functional roles of protein modification by small ubiquitin-like modifier (SUMO) proteins are not well understood compared to ubiquitination. Promyelocytic leukemia (PML) proteins are good substrates for SUMOylation, and PML-nuclear bodies (PML-NBs) may function as a platform for the PML SUMOylation. PML proteins are rapidly modified both with SUMO2/3 and SUMO1 after exposure to arsenite (As

Published
2021

Catalog

Books, media, physical & digital resources
See catalog results