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1. Distinctive features of bovine alphaherpesvirus types 1 and 5 and the virus-host interactions that might influence clinical outcomes.

Author

Marin M, Burucúa M, Rensetti D, Rosales JJ, Odeón A, and Pérez S

Subjects
Animals, Cattle, Humans, Cattle Diseases virology, Herpesviridae Infections veterinary, Herpesviridae Infections virology, Herpesvirus 1, Bovine pathogenicity, Herpesvirus 5, Bovine pathogenicity, Host-Pathogen Interactions physiology
Abstract

Bovine herpesvirus types 1 (BoHV-1) and 5 (BoHV-5) are two closely related alphaherpesviruses. BoHV-1 causes several syndromes in cattle, including respiratory disease and sporadic cases of encephalitis, whereas BoHV-5 is responsible for meningoencephalitis in calves. Although both viruses are neurotropic, they differ in their neuropathogenic potential. This review summarizes the findings on the specific mechanisms and pathways known to modulate the pathogenesis of BoHV-1 and BoHV-5, particularly in relation to respiratory and neurological syndromes, which characterize BoHV-1 and BoHV-5 infections, respectively.

Published
2020
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