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Your search keyword '"Guo, Jian"' showing total 1 results
Start Over Author "Guo, Jian" Search Limiters Peer Reviewed Publication Year Range Last 3 years Journal artificial cells, nanomedicine & biotechnology Publisher taylor & francis ltd

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1 results on '"Guo, Jian"'

1. Biomolecular assembly on interdigitated electrode nanosensor for selective detection of insulin-like growth factor-1.

Author

Gu, Yan, Liu, Lijie, Guo, Jian, Xiao, Shun, Fang, Fang, Yu, Xiaoyun, Gopinath, Subash C. B., Wu, Jianlie, and Liu, Xunqiang

Subjects
*SOMATOMEDIN, *CINNAMON, *APTAMERS, *ELECTRODES, *IMAGING systems, *ABDOMINAL aortic aneurysms, *ELECTROCHEMILUMINESCENCE
Abstract

This research is focussed to quantify IGF1 by electroanalytical analysis on InterDigitated electrode surface and characterized by the microscopic observations. For the detection, antibody and aptamer were used to analyze the level of IGF1. The sandwich pattern (aptamer-IGF1-antibody) was designed on the chemically modified IDE surface and reached the limit of detection to 10 fM with 100 folds enhancement in the sensitivity. Different control experiments (absence of IGF1, binding with IGF2 and with non-complementary aptamer) were failed to show the current changes, discriminated the specific detection. A good detection strategy is to complement the currently following imaging systems for AAA. [ABSTRACT FROM AUTHOR]

Published
2021
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