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1. [Studies of the blood pool dynamic actions of dipyridamole in pregnancy (author's transl)].

Author

Lippert TH, Cloeren SE, and Fridrich R

Subjects
Adult, Coronary Circulation drug effects, Female, Humans, Placenta blood supply, Regional Blood Flow drug effects, Uterus blood supply, Dipyridamole pharmacology, Hemodynamics drug effects, Pregnancy drug effects
Abstract

The action of 2,6-bis(diethanolamino)-4,8-dipiperidinopyrimido-(5,4-d)pyrimidine (dipyridamole, Persantin) on utero-placental and cardiac blood pool dynamics was examined in 12 pregnant women. 113mIndium was injected i.v. and blood pool changes in the heart, placenta and myometrium were registered by external measurement of the gamma-activity. While there was a significant decrease in blood pool of the heart after dipyridamole, there were no marked changes in the blood pools of placenta or myometrium. The decrease in cardiac blood pool was interpreted as a sign of an increase in the cardiac output.

Published
1979

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