11 results on '"Shin E"'
Search Results
2. Impact of tumor grade on pancreatic neuroendocrine tumors
- Author
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Shyr, Bor-Shiuan, Shyr, Bor-Uei, Chen, Shih-Chin, Shyr, Yi-Ming, and Wang, Shin-E
- Published
- 2022
- Full Text
- View/download PDF
3. Pancreas transplant with enteric drainage at a single institute in Asia
- Author
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Shih, Mu-Shan, Shyr, Bor-Uei, Shyr, Bor-Shiuan, Chen, Shih-Chin, Shyr, Yi-Ming, and Wang, Shin-E
- Published
- 2022
- Full Text
- View/download PDF
4. Operative results and patient satisfaction after robotic pancreaticoduodenectomy
- Author
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Shyr, Bor-Uei, Shyr, Bor-Shiuan, Chen, Shih-Chin, Chang, I-Wen, Shyr, Yi-Ming, and Wang, Shin-E.
- Published
- 2020
- Full Text
- View/download PDF
5. Impact of tumor grade on pancreatic neuroendocrine tumors
- Author
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Bor-Shiuan Shyr, Bor-Uei Shyr, Shih-Chin Chen, Yi-Ming Shyr, and Shin-E Wang
- Subjects
Male ,Pancreatic Neoplasms ,Neuroendocrine Tumors ,Infant, Newborn ,Humans ,Surgery ,Neoplasm Grading ,Prognosis ,Retrospective Studies - Abstract
Pancreatic neuroendocrine tumors (P-NETs) are highly heterogeneous with wide spectrum of biological behaviors and growth patterns. Here, we aimed to assess the impact of tumor grading on P-NETs prognosis and survival outcomes.Patients with P-NET were recruited to determine correlations between grades and clinicopathological factors, survival outcomes and prognostic factors.A total of 152 patients with P-NETs were enrolled. G1 P-NET were associated with significantly lower rates of perineural invasion, lymphovascular invasion, lymph node involvement and distant metastasis. The pancreatic head was the most common location of P-NETs. The 1-year, 5-year and 10-year overall survival rates of the patients were 94.4%, 89.1% and 78.8%, respectively. Majority of pancreatic neuroendocrine carcinoma (P-NEC) were unresectable (90.9%), and P-NECs patients had poor survival rates (1-year, 20% and no 5-year). Male sex, tumor size ≥2.5 cm, perineural invasion, lymph node invasion, metastasis, and advanced stage were significantly associated with poorer survival outcomes. Tumor grade and sex were independent survival predictors. Moreover, tumor grade was the most powerful prognostic factor.Tumor grade, sex, perineural invasion, tumor size, lymph node involvement, metastasis, and stage are survival predictors for patients with P-NETs. Tumor grade is the most powerful independent prognostic factor.
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- 2022
- Full Text
- View/download PDF
6. Pancreas transplant with enteric drainage at a single institute in Asia
- Author
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Bor-Uei Shyr, Bor-Shiuan Shyr, Mu-Shan Shih, Shin-E Wang, Shih-Chin Chen, and Yi-Ming Shyr
- Subjects
Graft Rejection ,medicine.medical_specialty ,Enteric drainage ,RD1-811 ,Pancreas graft ,Graft loss ,Malignancy ,Kidney transplant ,Pancreas after kidney transplant (PAK) ,Pancreas before kidney transplant (PBK) ,medicine ,Humans ,Pancreas ,Surgical complication ,business.industry ,Graft Survival ,medicine.disease ,Surgery ,Pancreas transplant alone (PTA) ,Survival Rate ,Simultaneous kidney pancreas transplant (SPK) ,medicine.anatomical_structure ,surgical procedures, operative ,Drainage ,Graft survival ,Pancreas Transplantation ,business - Abstract
Summary Background/objective This study is to assess immunological and graft survival outcomes after pancreas transplant at a single institute in Asia. Methods Patients undergoing pancreas transplant with enteric drainage were included. Clinical data and outcomes were evaluated and compared between each subgroup. Results There were 165 cases of pancreas transplant, including 38 (23 %) simultaneous pancreas-kidney transplant (SPK), 24 (15 %) pancreas after kidney transplant (PAK), 75 (46 %) pancreas transplant alone (PTA), and 28 (17 %) pancreas before kidney transplant (PBK). The overall surgical complication rate was 46.1 %, with highest (62.5 %) in PAK and lowest (32.0 %) in PTA, P = 0.008. The late complications included 32.7 % infection and 3.6 % malignancy. Overall rejection of pancreas graft was 24.8 % including 18.2 % acute and 9.7 % chronic rejection. Rejection was highest in PTA group (36.0 %) and lowest in PBK (3.6 %). There were 56 cases (33.9 %) with graft loss in total, with highest graft loss rate in PTA (38.7 %). The 1-year, 5-year and 10-year pancreas graft survivals for total patients were 98.0 %, 87.7 % and 70.9 % respectively. Conclusions Enteric drainage in pancreas transplant could be applied safely not only in SPK but also in other subgroups. Enteric drainage itself would not compromise the immunological and graft survival outcomes.
- Published
- 2021
7. Operative results and patient satisfaction after robotic pancreaticoduodenectomy
- Author
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I-Wen Chang, Bor-Shiuan Shyr, Shin-E Wang, Shih-Chin Chen, Yi-Ming Shyr, and Bor-Uei Shyr
- Subjects
Adult ,Male ,medicine.medical_specialty ,Chyle ,medicine.medical_treatment ,lcsh:Surgery ,Anastomotic Leak ,030230 surgery ,Pancreaticoduodenectomy ,03 medical and health sciences ,Pancreatic Fistula ,Young Adult ,0302 clinical medicine ,Patient satisfaction ,Postoperative Complications ,Robotic Surgical Procedures ,Surveys and Questionnaires ,medicine ,Humans ,Abscess ,Aged ,Aged, 80 and over ,Gastric emptying ,business.industry ,lcsh:RD1-811 ,Middle Aged ,medicine.disease ,Surgery ,Patient Outcome Assessment ,Treatment Outcome ,Pancreatic fistula ,Patient Satisfaction ,030220 oncology & carcinogenesis ,Pancreatectomy ,Quality of Life ,Feasibility Studies ,Female ,Complication ,business - Abstract
Summary: Background/Objective: There are no reports available on patient satisfaction and quality-of-life after robotic pancreaticoduodenectomy (RPD). This study aimed to evaluate not only surgical outcomes but also patient satisfaction after RPD. Methods: Prospectively collected data for RPD were analyzed for surgical outcomes. Questionnaires were sent to patients to assess patient satisfaction regarding RPD. Results: The study included 105 patients who underwent RPD, with 44 (41.9%) patients presenting with associated surgical complications. There were no significant differences between the without and with complication groups in median console time (390 min. Vs. 373 min.), blood loss (100 mL vs. 100 mL), and harvested lymph node number (14 vs. 15). There was no surgical mortality in this study. Major complications ≥ Clavien–Dindo III occurred in 7.6% of the total 105 RPD patients. The most common complication was chyle leakage (18.1%), followed by postoperative pancreatic fistula (5.7%), intra-abdominal abscess (4.8%), delayed gastric emptying (3.8%), and post pancreatectomy hemorrhage (3.8%). Almost all of the patients responded to this RPD-related survey with “fair” to “excellent” grades for all items, except 1 (
- Published
- 2019
8. Renal angiomyolipoma with tuberous sclerosis complex: How it differs from sporadic angiomyolipoma in both management and care
- Author
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Takashi Hatano and Shin Egawa
- Subjects
Renal angiomyolipoma ,Transcatheter arterial embolization ,Mammalian target of rapamycin inhibitor ,Tuberous sclerosis complex ,Hemorrhage ,Surgery ,RD1-811 - Abstract
Renal angiomyolipoma (AML) is the most common benign tumor of the kidney. It consists of blood vessels, smooth muscle and fat components in varying proportions. AML is divided into the sporadic type and tuberous sclerosis complex (TSC)-associated type. TSC-associated AML develops at a younger age and tends to exhibit a much faster growth rate over time than sporadic AML. AMLs are classified as classic AML, fat-poor AML and epithelioid AML. Epithelioid AML, though rare, shows aggressive behavior leading to distant metastasis and mortality. TSC-associated AML is more likely to have an epithelioid component than sporadic AML. Active surveillance is the suggested management for small AML. Clinical intervention is mainly indicated when there is a substantial risk of rupture. Minimally invasive therapies, including partial nephrectomy, transcatheter arterial embolization, and mammalian target of rapamycin (mTOR) inhibitor treatment are employed for patients who require treatment. An updated algorithm for the management of AML is herein described. According to this algorithm, treatment intervention is recommended for TSC-associated AML >3 cm, even in asymptomatic cases. In cases with asymptomatic sporadic AML >4 cm in size or with an intra-tumoral aneurysm of >5 mm, treatment, including transcatheter arterial embolization or partial nephrectomy, is advised. The major complication of AML is intra-tumoral or retroperitoneal hemorrhage due to rupture that may be serious and life threatening. Thus, correct diagnosis, proper observation, and appropriate treatment are very important in the management of renal AML.
- Published
- 2020
- Full Text
- View/download PDF
9. Survival and surgical outcomes of robotic versus open pancreatoduodenectomy for ampullary cancer: A propensity score-matching comparison
- Author
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Bor-Shiuan Shyr, Shin-E Wang, Shih-Chin Chen, Yi-Ming Shyr, and Bor-Uei Shyr
- Subjects
Ampullary cancer ,Pancreaticoduodenectomy ,Robotic ,Survival ,Surgery ,RD1-811 - Abstract
Background/objective: Robotic pancreaticoduodenectomy in ampullary cancer has never been studied. This study aimed to clarify the feasibility and justification of robotic pancreaticoduodenectomy in ampullary cancer in terms of surgical risks, and oncologic and survival outcomes. Methods: A propensity score-matching comparison of robotic and open pancreaticoduodenectomy based on seven factors commonly used to predict the survival outcomes in ampullary cancer patients. Results: A total of 147 patients were enrolled, of which 101 and 46 underwent robotic and open pancreaticoduodenectomies, respectively. After propensity score-matching with a 2:1 ratio, 88 and 44 patients in the robotic and open pancreaticoduodenectomy groups were included. The operation time was of no significant difference after matching. The median intraoperative blood loss was much less in those who underwent robotic pancreaticoduodenectomy, both before (median, 120 vs. 320 c.c. P
- Published
- 2024
- Full Text
- View/download PDF
10. Pancreas transplant with enteric drainage at a single institute in Asia
- Author
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Mu-Shan Shih, Bor-Uei Shyr, Bor-Shiuan Shyr, Shih-Chin Chen, Yi-Ming Shyr, and Shin-E Wang
- Subjects
Pancreas before kidney transplant (PBK) ,Pancreas after kidney transplant (PAK) ,Simultaneous kidney pancreas transplant (SPK) ,Pancreas transplant alone (PTA) ,Surgery ,RD1-811 - Abstract
Summary: Background/objective: This study is to assess immunological and graft survival outcomes after pancreas transplant at a single institute in Asia. Methods: Patients undergoing pancreas transplant with enteric drainage were included. Clinical data and outcomes were evaluated and compared between each subgroup. Results: There were 165 cases of pancreas transplant, including 38 (23 %) simultaneous pancreas-kidney transplant (SPK), 24 (15 %) pancreas after kidney transplant (PAK), 75 (46 %) pancreas transplant alone (PTA), and 28 (17 %) pancreas before kidney transplant (PBK). The overall surgical complication rate was 46.1 %, with highest (62.5 %) in PAK and lowest (32.0 %) in PTA, P = 0.008. The late complications included 32.7 % infection and 3.6 % malignancy. Overall rejection of pancreas graft was 24.8 % including 18.2 % acute and 9.7 % chronic rejection. Rejection was highest in PTA group (36.0 %) and lowest in PBK (3.6 %). There were 56 cases (33.9 %) with graft loss in total, with highest graft loss rate in PTA (38.7 %). The 1-year, 5-year and 10-year pancreas graft survivals for total patients were 98.0 %, 87.7 % and 70.9 % respectively. Conclusions: Enteric drainage in pancreas transplant could be applied safely not only in SPK but also in other subgroups. Enteric drainage itself would not compromise the immunological and graft survival outcomes.
- Published
- 2022
- Full Text
- View/download PDF
11. Operative results and patient satisfaction after robotic pancreaticoduodenectomy
- Author
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Bor-Uei Shyr, Bor-Shiuan Shyr, Shih-Chin Chen, I-Wen Chang, Yi-Ming Shyr, and Shin-E. Wang
- Subjects
Surgery ,RD1-811 - Abstract
Summary: Background/Objective: There are no reports available on patient satisfaction and quality-of-life after robotic pancreaticoduodenectomy (RPD). This study aimed to evaluate not only surgical outcomes but also patient satisfaction after RPD. Methods: Prospectively collected data for RPD were analyzed for surgical outcomes. Questionnaires were sent to patients to assess patient satisfaction regarding RPD. Results: The study included 105 patients who underwent RPD, with 44 (41.9%) patients presenting with associated surgical complications. There were no significant differences between the without and with complication groups in median console time (390 min. Vs. 373 min.), blood loss (100 mL vs. 100 mL), and harvested lymph node number (14 vs. 15). There was no surgical mortality in this study. Major complications ≥ Clavien–Dindo III occurred in 7.6% of the total 105 RPD patients. The most common complication was chyle leakage (18.1%), followed by postoperative pancreatic fistula (5.7%), intra-abdominal abscess (4.8%), delayed gastric emptying (3.8%), and post pancreatectomy hemorrhage (3.8%). Almost all of the patients responded to this RPD-related survey with “fair” to “excellent” grades for all items, except 1 (
- Published
- 2020
- Full Text
- View/download PDF
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