1. Clinical Outcomes of Cases with Absent Cervical Dysplasia in Cold Knife Conization Specimens
- Author
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Tayfun Gungor, Nilufer Cetinkaya, Levent Sirvan, Selçuk Erkılınç, Eralp Baser, Salim Erkaya, Emre Özgü, and Hakan Raşit Yalçin
- Subjects
Cancer Research ,medicine.medical_specialty ,Epidemiology ,business.industry ,Public Health, Environmental and Occupational Health ,Retrospective cohort study ,Cold knife ,medicine.disease ,Cervical intraepithelial neoplasia ,Tertiary referral hospital ,female genital diseases and pregnancy complications ,Cervical biopsy ,Surgery ,Oncology ,Dysplasia ,medicine ,Carcinoma ,sense organs ,Human papillomavirus ,business - Abstract
Background: Cold knife conization is a surgical procedure that allows both diagnosis and treatment of cervical lesions at the same time. It is mainly performed for indications of high-grade cervical intraepithelial neoplasia (CIN). In this study, we aimed to investigate the clinical outcome of cases without CIN in cold knife conization specimen, following a high-grade lesion (CIN2/3) in cervical biopsy. Materials and Methods: We performed a retrospective cohort study at a tertiary referral hospital between January 1 st 2008 and August 1 st 2012. Cases that underwent cold knife conization for CIN2/3 within the study period were included. Cone-negative (Group 1) and cone-positive (Group 2) cases were analyzed for various clinical parameters, and were compared in the 1-year post-conization period for histological recurrence and human papillomavirus (HPV) DNA status. Results: A total of 173 women underwent cold knife conization for CIN2/3 within the study period. Twenty-two cases (12.7%)
- Published
- 2013
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