Search

Your search keyword '"Leonard Pinchuk"' showing total 2 results
Start Over Author "Leonard Pinchuk" Journal asme 2008 summer bioengineering conference, parts a and b
2 results on '"Leonard Pinchuk"'

1. In Vivo Evaluation of Composite Polymeric Materials for Potential Application in a Trileaflet Heart Valve

Author

Qiang Wang, Siobhain Lynn Gallocher, Amit Datye, Richard T. Schoephoerster, and Leonard Pinchuk

Subjects
Materials science, Valve leaflet, medicine.anatomical_structure, Biocompatibility, parasitic diseases, Composite number, technology, industry, and agriculture, Polymer composites, medicine, social sciences, Heart valve, Composite material, Biocompatible material
Abstract

The novel trileaflet heart valve that is presently undergoing investigation is a composite design of a proprietary polymer (SIBS), with an embedded fabric. SIBS had been shown to be a biocompatible, oxidatively stable polymer, and by adopting the natural valve leaflet design (reinforcement fabric), the SIBS trileaflet valve has the potential to have outstanding hemodynamic performance, durability, and biocompatibility [1,2].Copyright © 2008 by ASME

Published
2008
Full Text
View/download PDF

2. Effect of Leaflet Anisotropy, Coaptation Curvature, and Stent Flexibility on the Stress Concentrations and In Vitro Function of Polymer Trileaflet Heart Valves

Author

Kuang-Hsi Wu, Siobhain Lynn Gallocher, Richard T. Schoephoerster, Amit Datye, and Leonard Pinchuk

Subjects
chemistry.chemical_classification, Flexibility (anatomy), medicine.anatomical_structure, Materials science, chemistry, medicine.medical_treatment, medicine, Stent, Polymer, Heart valve, Biomedical engineering, Stress concentration
Abstract

Polymer trileaflet valves have been under investigation for the past 40–50 years in an attempt to produce a valve alternative that is both durable and non-thrombogenic. Most have met with limited success due to oxidative reactions and high dynamic stresses borne by the material [1]. With this knowledge, an oxidatively stable polyolefin, poly(styrene-b-isobutylene-b-styrene) (SIBS), was selected for the design of a fiber-reinforced polymer trileaflet heart valve. The hydrodynamic properties of prototype SIBS valves have been encouraging, but some valves failed prematurely as a result of insufficient durability during in vivo implantation in a sheep model or during accelerated in vitro fatigue.

Published
2008
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results