12 results on '"Malhi G"'
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2. The science and practice of lithium therapy
- Author
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Malhi Gin S.
- Published
- 2012
Catalog
3. Concerns over the process and outcomes of the review by the Royal Australian and New Zealand College of Psychiatrists into long-term psychodynamic psychotherapy.
- Author
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Kisely S and Malhi G
- Abstract
Competing Interests: Declaration of Conflicting InterestsThe author(s) declared the following potential conflicts of interest with respect to the research, authorship and/or publication of this article: S.K. was a member of the RANZCP Board from May to September 2024. However, he had no involvement in either the process and outcomes of the College review into LTPP for mood disorders, including the decision to approve the AFC report. GM was first author of the RANZCP Clinical Practice Guideline (CPG) for mood disorders. more...
- Published
- 2025
- Full Text
- View/download PDF
4. Getting emotional about affect and mood.
- Author
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Kaufmann C, Agalawatta N, Bell E, and S Malhi G
- Subjects
- Humans, Affect, Emotions
- Published
- 2020
- Full Text
- View/download PDF
5. The Psychiatry Ashes Test: July update.
- Author
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Boyce P and Malhi G
- Published
- 2018
- Full Text
- View/download PDF
6. Why repetitive transcranial magnetic stimulation should be available for treatment resistant depression.
- Author
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Galletly CA, Loo CK, Malhi GS, Mitchell PB, and Fitzgerald P
- Subjects
- Humans, Depressive Disorder, Treatment-Resistant therapy, Transcranial Magnetic Stimulation methods
- Published
- 2015
- Full Text
- View/download PDF
7. Amphetamine availability and admissions for psychosis in New South Wales, 2001-2009.
- Author
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Sara G, Burgess P, Malhi G, and Whiteford H
- Subjects
- Adolescent, Adult, Aged, Diagnosis, Dual (Psychiatry) statistics & numerical data, Drug and Narcotic Control statistics & numerical data, Humans, Mental Health Services statistics & numerical data, Middle Aged, New South Wales epidemiology, Amphetamines adverse effects, Hospitalization trends, Psychoses, Substance-Induced epidemiology
- Abstract
Objective: Clinicians have raised concerns about the impact of amphetamines on demand for mental health services. However, evidence for this link is limited. This study explores whether changes in the availability of amphetamines in NSW in the last decade have been associated with variations in admission to mental health units for amphetamine related conditions and for psychoses more generally., Method: The study examined admissions from community settings to NSW acute mental health units from 2000 to 2009. Quarterly rates of hospital admission with primary or comorbid diagnoses of stimulant use disorders, stimulant-induced psychoses and non-drug-related psychoses were compared to quarterly rates of criminal incidents of amphetamine possession and use, which provide an indirect measure of the community availability of amphetamines. Analysis was confounded by increases in mental health beds over the period. Linear regression predicted admission rates on the basis of amphetamine availability, adjusting for changing mental health bed numbers., Results: Amphetamine availability and admissions for psychoses increased steadily from 2000 to a peak in early 2007, but have declined since. Regression models including both amphetamine availability and bed numbers predicted 34% of variation in stimulant use disorders admission rates and 50% of variation in stimulant induced psychoses admission rates. There was no significant effect of amphetamine availability on admissions for schizophrenia and other non-drug-induced psychoses after controlling for changing bed numbers., Conclusions: Increased amphetamine availability appears to have been one factor increasing demand for mental health admission in NSW over the last decade. However, there appears to have been a recent downward trend in both amphetamine availability and amphetamine-related admissions. Policies which reduce the community availability of amphetamines may result in reduced admissions for amphetamine-related mental health conditions, including amphetamine-induced psychoses. Further research is needed regarding effects of amphetamine availability on admissions for schizophrenia. more...
- Published
- 2011
- Full Text
- View/download PDF
8. Self-harming in depressed patients: pattern analysis.
- Author
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Parker G, Malhi G, Mitchell P, Kotze B, Wilhelm K, and Parker K
- Subjects
- Adult, Alcoholism psychology, Anxiety Disorders epidemiology, Anxiety Disorders psychology, Child, Child Abuse psychology, Child Abuse, Sexual psychology, Female, Humans, Male, Odds Ratio, Parents psychology, Personality Disorders psychology, Socioeconomic Factors, Stress, Psychological psychology, Substance-Related Disorders psychology, Depressive Disorder psychology, Self-Injurious Behavior psychology
- Abstract
Objective: As deliberate self-harm (DSH) is a common concomitant of depressive disorders, we undertook a study examining the relevance of possible determinants and correlates of DSH., Method: Three separate samples of depressed outpatients were studied to determine consistency of identified factors across samples, with principal analyses involving gender, age and diagnosis-matched DSH and non-DSH subjects., Results: Across the samples, some 20% of subjects admitted to episodes of DSH. Women reported higher rates and there was a consistent trend for higher rates in bipolar patients. Univariate analyses examined the relevance of several sociodemographic variables, illicit drug and alcohol use, past deprivational and abusive experiences, past suicidal attempts and disordered personality functioning. Multivariate analyses consistently identified previous suicide attempts and high 'acting out' behaviours across the three samples, suggesting the relevance of an externalizing response to stress and poor impulse control., Conclusions: Results assist the identification and management of depressed patients who are at greater risk of DSH behaviours. more...
- Published
- 2005
- Full Text
- View/download PDF
9. Schema-focused cognitive therapy for bipolar disorder: reducing vulnerability to relapse through attitudinal change.
- Author
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Ball J, Mitchell P, Malhi G, Skillecorn A, and Smith M
- Subjects
- Adaptation, Psychological, Humans, Life Change Events, Risk Factors, Secondary Prevention, Sick Role, Attitude to Health, Bipolar Disorder therapy, Cognitive Behavioral Therapy methods
- Abstract
Objective: Acceptance of, and adaptability to illness, are major determinants of adherence to treatment and functional recovery. This paper addresses the major psychosocial factors associated with bipolar disorder and the role of psychological interventions in symptom management and adaptability to the illness experience. A new model is presented highlighting the role of developmental experiences and temperament in determining reactions to bipolar disorder. The authors propose that by addressing reactions to the illness experiences and effects on self-concept through schema-focused cognitive therapy, functional recovery is more likely to occur among those patients functioning below expectation., Method: A systematic review of the current literature including an Index Medicus/MEDLINE search was conducted, focusing on risk factors, cognitive vulnerabilities and triggers associated with bipolar disorder. Psychological treatments available for the treatment of bipolar disorder are reviewed and details of a novel schema-focused cognitive model for this condition are presented. Traditional models of adaptation to chronic illness are outlined and incorporated into the proposed model. Schema-focused cognitive therapy is proposed as an approach to help patients reduce cognitive vulnerability to relapse in addition to adopting effective mood management strategies., Results and Conclusions: There is a need for psychological treatments which reduce the risks associated with poor functionality in patients with bipolar disorder. Schema-focused cognitive therapy specifically targets the temperament, developmental experiences and cognitive vulnerabilities that determine adjustment to illness. This proposed treatment, combined with pharmacotherapy, may offer new psychotherapeutic options for the future. more...
- Published
- 2003
- Full Text
- View/download PDF
10. Valid assessment of the clinical features of depression by relatives appears to slip under the RADAR.
- Author
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Parker G, Gladstone G, Mitchell P, Wilhelm K, Malhi G, and Loo C
- Subjects
- Adult, Depressive Disorder, Major epidemiology, Female, Health Personnel, Humans, Judgment, Male, Observer Variation, Reproducibility of Results, Severity of Illness Index, Depressive Disorder, Major diagnosis, Depressive Disorder, Major psychology, Family, Surveys and Questionnaires
- Abstract
Objective: We report on the development of an observational measure designed for completion by relatives, the Recent Appearance of Depression Assessed by Relatives (RADAR), and consider its validity., Method: One hundred and one patients with a current major depressive episode had a relative or close friend complete the RADAR, while psychiatrists and research assistants collected extensive data., Results: Correlated against both patient self-report and psychiatrist-rated depression severity measures, RADAR scores evidenced poor validity overall. Recent Appearance of Depression Assessed by Relatives scores also failed to differentiate depressive subtypes, in that scores for patients with melancholic depression were not significantly higher than for those with non-melancholic depression., Conclusions: Results are consistent with previous findings of poor agreement between clinicians and corroborative witnesses in assessing clinical depressive features, and argue against reliance on corroborative witness reports. more...
- Published
- 2003
- Full Text
- View/download PDF
11. Are atypical antipsychotic drugs also atypical antidepressants?
- Author
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Parker G and Malhi G
- Subjects
- Adult, Antidepressive Agents, Second-Generation administration & dosage, Antipsychotic Agents administration & dosage, Bipolar Disorder drug therapy, Depressive Disorder complications, Depressive Disorder, Major drug therapy, Drug Therapy, Combination, Female, Humans, Male, Middle Aged, Psychomotor Agitation etiology, Treatment Outcome, Antidepressive Agents, Second-Generation therapeutic use, Antipsychotic Agents therapeutic use, Depressive Disorder drug therapy
- Abstract
Objective: To report a case series and review the psychopharmacology of the neuroleptic drugs to suggest that the atypical antipsychotic drugs may have an antidepressant action, at least for those patients with the melancholic subtype., Method: We note the literature suggesting that the older (or typical) antipsychotic drugs were established as having antidepressant activity, describe an open study of some two dozen patients with a treatment-resistant melancholic depression, describe rapid resolution of depression and augmentation benefits associated with commencing an atypical antipsychotic drug in a percentage of subjects, and then review relevant psychopharmacological studies to consider whether there is a rationale for use of antipsychotic drugs to treat depression., Results: Of some two dozen patients treated with an atypical antipsychotic drug, almost immediate improvement was noted in four patients, and evidence of augmentation benefit obtained in another three patients., Conclusions: Impressions from this case series are encouraging. However, as open clinical observational studies are problematic, controlled studies are required to establish whether the atypical antipsychotic drugs have a role in the management of certain expressions of depression, and, in particular, treatment-resistant melancholic depression. more...
- Published
- 2001
- Full Text
- View/download PDF
12. 'Why getting fat, Doc?' Weight gain and psychotropic medications.
- Author
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Malhi GS, Mitchell PB, and Caterson I
- Subjects
- Humans, Obesity prevention & control, Psychotropic Drugs therapeutic use, Risk Factors, Mental Disorders drug therapy, Obesity chemically induced, Psychotropic Drugs adverse effects, Weight Gain drug effects
- Abstract
Objectives: Weight gain associated with the use of psychotropic medications is a common clinical problem that is of particular importance because of its effects on the general health of psychiatric patients and their compliance with treatment. This paper aims to explore this issue and discuss the mechanisms of weight gain and methods of prevention., Method: A literature review (Index Medicus/Medline) was carried out as well as a review of other relevant papers and data known to the authors., Results: Significant weight gain may result in considerable morbidity. The majority of psychotropic medications are associated with weight gain, however, the mechanisms of weight gain are often complex and poorly understood., Conclusion: Clinically, weight gain can be anticipated and often managed with some success in the majority of psychiatric patients with simple but relatively effective measures. It is important for clinicians to be aware of this common clinical problem and educate patients from the outset, monitoring them regularly and intervening when necessary. more...
- Published
- 2001
- Full Text
- View/download PDF
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