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Introduction: This study aimed to review the clinical characteristics and outcomes of COVID-19 patients presented with in-hospital hyperglycemia or pre-existing type 2 diabetes (T2DM) Methods: This is a retrospective study conducted in Fatmawati General Hospital, Indonesia, from March 18th-Apr 30th, 2020 We reviewed medical records of 27 COVID-19 patients presented with either in-hospital hyperglycemia (11, 12 2%) or pre-existing T2DM (16, 17 8%) from a total of 90 confirmed COVID-19 cases admitted in our hospital Results: Critical conditions occurred in 50% of T2DM and 54 55% of the in-hospital hyperglycemia group Mortality was documented in 68 75% of T2DM and 81 82% of in-hospital hyperglycemia group Hypoglycemia, diabetic ketoacidosis, lactic acidosis and ketosis were found in 12 5%, 25%, 18 75%, and 25% of individuals with T2DM, respectively, resulting in a high mortality rate Meanwhile, diabetes-related complications were rare among the in-hospital hyperglycemia group However, respiratory failure (45 45% vs 6 25%) and septic shock (27 27% vs 6 25%) were more frequent than in the T2DM group Conclusion: In this preliminary study, a high mortality rate was documented among COVID-19 patients with preexisting T2DM and in-hospital hyperglycemia In T2DM subjects, diabetes related complications contributed to a higher mortality rate, while in hospital hyperglycemia group, respiratory failure and septic shock were more frequent © 2020, Sanglah General Hospital All rights reserved