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Start Over Author "Tang, Yan" Topic abca1 Topic gene expression Journal biochemical & biophysical research communications

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1 results on '"Tang, Yan"'

1. Growth differentiation factor-15 induces expression of ATP-binding cassette transporter A1 through PI3-K/PKCζ/SP1 pathway in THP-1 macrophages.

Author

Wu, Jian-Feng, Wang, Yan, Zhang, Min, Tang, Yan-Yan, Wang, Bo, He, Ping-Ping, Lv, Yun-Cheng, Ouyang, Xin-Ping, Yao, Feng, Tan, Yu-Lin, Tang, Shi-Lin, Tang, Deng-Pei, Cayabyab, Francisco S., Zheng, Xi-Long, Zhang, Da-Wei, Zeng, Gao-Feng, and Tang, Chao-Ke

Subjects
*GROWTH factors, *GENE expression, *ATP-binding cassette transporters, *PHOSPHOINOSITIDES, *MACROPHAGES, *CHOLESTEROL
Abstract

Highlights: [•] We observed that GDF-15 promotes cholesterol efflux in THP-1 macrophages. [•] GDF-15 induces ABCA1 expression via PI3K/PKCζ/SP1 signaling pathway. [•] The paper first time explains the regulation mechanism of GDF-15-induced ABCA1 expression. [ABSTRACT FROM AUTHOR]

Published
2014
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