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Your search keyword '"Namba, Akiko"' showing total 1 results
Start Over Author "Namba, Akiko" Journal biochemical & biophysical research communications
1 results on '"Namba, Akiko"'

1. Food additive succinate exacerbates experimental autoimmune encephalomyelitis accompanied by increased IL-1β production.

Author

Sugiyama, Yasuko, Takata, Kazushiro, Kinoshita, Makoto, Motooka, Daisuke, Shiraishi, Naoyuki, Kihara, Keigo, Murata, Hisashi, Beppu, Shohei, Koda, Toru, Yamashita, Kazuya, Namba, Akiko, Fujimoto, Kosuke, Kumanogoh, Atsushi, Okuno, Tatsusada, and Mochizuki, Hideki

Subjects
*FOOD additives, *ENCEPHALOMYELITIS, *DISEASE exacerbation
Abstract

• Oral intake of succinate exacerbates the clinical course of EAE. • Oral intake of succinate has distinct effect on the gene signature of CNS-resident cells. • Exacerbation of EAE by oral intake of succinate is independent of CNS-resident cells. • Extracellular succinate augments IL-1β production and induces Th17 differentiation. [ABSTRACT FROM AUTHOR]

Published
2023
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