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Start Over Author "Garver FA" Journal biochemical medicine
4 results on '"Garver FA"'

2. The production of prostaglandins with an erythropoietin generating factor(s).

Author

Neal WA, Lewis JP, Garver FA, and Lutcher CL

Subjects
Animals, Erythropoiesis drug effects, Fatty Acids metabolism, Female, Humans, Mice, Mice, Inbred AKR, Prostaglandins A biosynthesis, Prostaglandins A pharmacology, Prostaglandins D biosynthesis, Prostaglandins D pharmacology, Prostaglandins E biosynthesis, Prostaglandins E pharmacology, Prostaglandins F biosynthesis, Prostaglandins F pharmacology, Erythropoietin biosynthesis, Prostaglandins biosynthesis
Published
1980
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4. Partial characterization of an erythropoiesis inhibitory factor.

Author

Neal WA, Garver FA, Lewis JP, Gardner E Jr, and Lutcher CL

Subjects
Countercurrent Distribution, Dinoprost, Humans, Immunoelectrophoresis, Molecular Weight, Prostaglandins F urine, Blood Proteins urine
Abstract

An inhibitory factor of erythropoiesis, obtained from normal human urine, is indicated to be a complex of a fragment of alpha 1-acid glycoprotein and prostaglandin F2 alpha. Immunoelectrophoresis reveals two protein components in the EIF complex which separate during acrylamide gel electrophoresis. A gamma-globulin (MW 185,000) is a carrier of the complex. A fragment of alpha 1-acid glycoprotein (MW 9300) retains the inhibitory factor, PGF2 alpha. Noncovalent forces bind the PGF2 alpha to the protein, and PGF2 alpha can be extracted with benzene.

Published
1985
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