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Summary A selected series of 33 monosubstituted nitrobenzenes, which were from commercial sources or synthesized by known methods, was tested for algicidic activity against autotrophic Chlorella vulgaris suspensions. Isoactive inhibitory values pc501) were determined from dosageeffectivness relations and used as activity parameters for structure-activity correlations. Simple and multiple regression equations are reported, discussed and compared with analogous QSAR of earlier tested series. Two separate functions have been found for meta-, para-, and ortho-derivatives.