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The dynamics of the motion of a complex polysaccharide with seven sugar residues in the repeating subunit and which is a receptor for lectin interaction in the coaggregation of oral bacteria, were investigated. Findings indicated the polymer to be highly flexible with a hinge at (1->6)-linked galactofuranoside residue. Several different techniques of data analysis were employed including a reduced spectral density function technique as well as several different techniques in which a series of isotropically decaying rotational correlation functions were assumed.

A technique for constructing conformational models of flexible complex polysaccharides on the basis of NMR data and molecular modeling is shown and used on a polysaccharide which is a lectin-binding receptor significant in coaggregation of oral bacteria. The method involves uniform biosynthetic enrichment of the polysaccharide with 13C which permits accurate measurements of heteronuclear coupling constraints from a three-dimensional coupled HMQC-NOESY spectrum.

Investigates the involvement of univalent cations in stabilizing G-quartet structures of the oligonucleotide d(T2G4T). Synthesizing of oligonucleotide; Nuclear magnetic resonance measurements; Smear of electron density; Types of binding environments for univalent cations; NMR behaviors of 23Na+ and 39K+; Potassium; Resonances of amino protons.

Examines assumptions about duplex DNA structure. Sensitivity to ionic conditions; Binding of simple cations to DNA in a nonspecific fashion; Experimental procedures; Oligonucleotides; Quadrupole coupling constants.