1. Isolation and Identification of a New Thymic Peptide from Calf Thymus.
- Author
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Xi-Ming Qin, Ming-Xing Duan, Bin Deng, Xi-Cheng Liu, Qiang-Zhe Zhang, Zheng Liu, and Hong-Xuan He
- Subjects
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PEPTIDES , *T cells , *THYMUS , *AMINO acid sequence , *MOLECULAR weights , *CALVES - Abstract
Various thymic peptides (including thymulin, thymic humoral factor, thymopoietin, etc.) play important roles in the process of T cell maturation and development. We isolated a new peptide from calf thymus and named it thymus activity factor II (TAF-II). A yield of 0.92 mg of TAF-II was purified from 500 g calf thymus. Analysis by LC/MSD-Trap showed the amino acid sequence of this hexapeptide to be Glu-Ala-Lys-Ser-Gln-Gly-OH with molecular weight 618.5 daltons. We have also begun to investigate the influence of TAF-II. [ABSTRACT FROM AUTHOR]
- Published
- 2004
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