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Your search keyword '"Tito, Calì"' showing total 2 results
Start Over Author "Tito, Calì" Journal biochimica et biophysica acta. molecular basis of disease
2 results on '"Tito, Calì"'

1. Tau localises within mitochondrial sub-compartments and its caspase cleavage affects ER-mitochondria interactions and cellular Ca

Author

Domenico, Cieri, Mattia, Vicario, Francesca, Vallese, Beatrice, D'Orsi, Paola, Berto, Alessandro, Grinzato, Cristina, Catoni, Diego, De Stefani, Rosario, Rizzuto, Marisa, Brini, and Tito, Calì

Subjects
Neurons, Mice, Cytosol, Alzheimer Disease, Caspases, Animals, Humans, Calcium, tau Proteins, Endoplasmic Reticulum, HeLa Cells, Mitochondria
Abstract

Intracellular neurofibrillary tangles (NFT) composed by tau and extracellular amyloid beta (Aβ) plaques accumulate in Alzheimer's disease (AD) and contribute to neuronal dysfunction. Mitochondrial dysfunction and neurodegeneration are increasingly considered two faces of the same coin and an early pathological event in AD. Compelling evidence indicates that tau and mitochondria are closely linked and suggests that tau-dependent modulation of mitochondrial functions might be a trigger for the neurodegeneration process; however, whether this occurs either directly or indirectly is not clear. Furthermore, whether tau influences cellular Ca

Published
2018

2. The ataxia related G1107D mutation of the plasma membrane Ca

Author

Tito, Calì, Martina, Frizzarin, Laura, Luoni, Francesco, Zonta, Sergio, Pantano, Carlos, Cruz, Maria Cristina, Bonza, Ilenia, Bertipaglia, Maria, Ruzzene, Maria Ida, De Michelis, Nunzio, Damiano, Oriano, Marin, Ginevra, Zanni, Giuseppe, Zanotti, Marisa, Brini, Raffaele, Lopreiato, and Ernesto, Carafoli

Subjects
Models, Molecular, Plasma Membrane Calcium-Transporting ATPases, Calmodulin, Humans, Point Mutation, Ataxia, Calcium Signaling
Abstract

The plasma membrane Ca

Published
2016

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