1. Recombination between RNA viruses and plasmids might have played a central role in the origin and evolution of small DNA viruses
- Author
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Mart Krupovic, Biologie Moléculaire du Gène chez les Extrêmophiles (BMGE), Institut Pasteur [Paris] (IP), I would like to thank Drs. Purificacion Lopez‐Garcia and Andrew Moore for inviting me to write this commentary., and Institut Pasteur [Paris]
- Subjects
viruses ,[SDV]Life Sciences [q-bio] ,Genome, Viral ,Biology ,Origin of replication ,Genome ,General Biochemistry, Genetics and Molecular Biology ,Evolution, Molecular ,03 medical and health sciences ,chemistry.chemical_compound ,Plasmid ,MESH: Plasmids ,[SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN] ,RNA Viruses ,MESH: Models, Genetic ,Gene ,MESH: Evolution, Molecular ,030304 developmental biology ,Genetics ,Recombination, Genetic ,0303 health sciences ,Models, Genetic ,030306 microbiology ,DNA Viruses ,RNA ,MESH: DNA Viruses ,chemistry ,Viral replication ,Viral evolution ,[SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology ,MESH: Recombination, Genetic ,MESH: Genome, Viral ,MESH: RNA Viruses ,DNA ,Plasmids - Abstract
International audience; The finding that viruses with RNA and DNA genomes can recombine to produce chimeric entities provides valuable insights into the origin and evolution of viruses. It also substantiates the hypothesis that certain groups of DNA viruses could have emerged from plasmids via acquisition of capsid protein-coding genes from RNA viruses.
- Published
- 2012
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