1. Analysis ofCYP450gene allelic variants can predict ifosfamide toxicity in Mexican paediatric patients
- Author
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Rocío Cárdenas-Cardós, Juan Luis Chávez-Pacheco, Marta Zapata-Tarrés, Armando de Uña-Flores, Antonio Álvaro-Heredia, Luz María Torres Espíndola, Israel Torres-Ramirez de Arellano, Julio Granados, Manuel de Jesús Castillejos López, Daniela Rojo-Serrato, Martín Pérez-García, Citlaltepetl Salinas-Lara, and Arnoldo Aquino-Gálvez
- Subjects
Oncology ,medicine.medical_specialty ,Ifosfamide ,business.industry ,Health, Toxicology and Mutagenesis ,Clinical Biochemistry ,030204 cardiovascular system & hematology ,Biochemistry ,03 medical and health sciences ,0302 clinical medicine ,Systemic toxicity ,030220 oncology & carcinogenesis ,Internal medicine ,Toxicity ,medicine ,Allele ,business ,Gene ,Paediatric patients ,medicine.drug - Abstract
Context: Ifosfamide (IFA) is an effective antineoplastic for solid tumours in children, although it is associated with high levels of systemic toxicity and causes death in some cases. Objective: Th...
- Published
- 2020
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