1. Histological and Histomorphometric Human Results of HA-Beta-TCP 30/70 Compared to Three Different Biomaterials in Maxillary Sinus Augmentation at 6 Months: A Preliminary Report
- Author
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Susanna Annibali, Antonella Polimeni, Carlo Mangano, Gian Luca Sfasciotti, Iole Vozza, Gerardo La Monaca, Giovanna Iezzi, and Maria Paola Cristalli
- Subjects
Adult ,Calcium Phosphates ,Male ,Sinus Floor Augmentation ,Maxillary sinus ,Article Subject ,Dentistry ,Connective tissue ,lcsh:Medicine ,Pilot Projects ,General Biochemistry, Genetics and Molecular Biology ,histology ,bone regeneration ,Preliminary report ,medicine ,sinus augmentation ,Humans ,Close contact ,Sinus (anatomy) ,Histological examination ,Aged ,Beta tcp ,Bone Transplantation ,General Immunology and Microbiology ,business.industry ,lcsh:R ,biphasic calcium phosphate ceramics ,grafting materials ,biomaterials ,General Medicine ,Maxillary Sinus ,Middle Aged ,medicine.anatomical_structure ,Durapatite ,Treatment Outcome ,Bone Substitutes ,Clinical Study ,Female ,business - Abstract
Objective. The aim of this investigation was to examine the bone regenerative potential of newly biphasic calcium phosphate ceramics (HA-β-TCP 30/70), by assessing histological and histomorphometric results of human specimens retrieved from sinuses augmented with HA-β-TCP 30/70, and comparing them to anorganic bovine bone (ABB), mineralized solvent-dehydrated bone allograft (MSDBA), and equine bone (EB), after a healing period of 6 months.Materials and Methods. Four consecutive patients with edentulous atrophic posterior maxilla were included in this report. A two-stage procedure was carried out for sinus augmentation with HA-β-TCP 30/70, ABB, MSDBA, and EB. After 6 months, specimens were retrieved at the time of implant placement and processed for histological and histomorphometric analyses.Results. At histological examination, all biomaterials were in close contact with the newly formed bone and showed the same pattern of bone formation; the grafted granules were surrounded by a bridge-like network of newly formed bone. A limited number of ABB particles were partially covered by connective tissue. The histomorphometric analysis revealed 30.2% newly formed bone for Ha-β-TCP 30/70, 20.1% for ABB, 16.4% for MSDBA, and 21.9% for EB.Conclusions. Within the limitations of the present investigation, these results support the successful use of HA-β-TCP 30/70 for sinus augmentation.
- Published
- 2014