1. Defining microchannels and valves on a hydrophobic paper by low-cost inkjet printing of aqueous or weak organic solutions
- Author
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Biyu Yuan, Longfei Cai, Minghua Zhong, Huolin Li, and Chunxiu Xu
- Subjects
Fluid Flow and Transfer Processes ,Aqueous solution ,Materials science ,Fabrication ,Filter paper ,Microfluidics ,Biomedical Engineering ,Diagnostic test ,Nanotechnology ,Condensed Matter Physics ,chemistry.chemical_compound ,Colloid and Surface Chemistry ,chemistry ,General Materials Science ,Fabrication and Laboratory Methods ,Cellulose ,Inkjet printing ,Microfabrication - Abstract
We describe a simple and cost-effective strategy for rapid fabrication of microfluidic paper-based analytical devices and valves by inkjet printing. NaOH aqueous solution was printed onto a hydrophobic filter paper, which was previously obtained by soaking in a trimethoxyoctadecylsilane-heptane solution, allowing selective wet etching of hydrophobic cellulose to create hydrophilic-hydrophobic contrast with a relatively good resolution. Hexadecyltrimethylammonium bromide (CTMAB)-ethanol solution was printed onto hydrophobic paper to fabricate temperature-controlled valves. At low temperature, CTMAB deposited on the paper is insoluble in aqueous fluid, thus the paper remains hydrophobic. At high temperature, CTMAB becomes soluble so the CTMAB-deposited channel becomes hydrophilic, allowing the wicking of aqueous solution through the valve. We believe that this strategy will be very attractive for the development of simple micro analytical devices for point-of-care applications, including diagnostic testing, food safety control, and environmental monitoring.
- Published
- 2015