Search

Your search keyword '"Kubatka, Peter"' showing total 19 results
Start Over Author "Kubatka, Peter" Journal biomolecules
19 results on '"Kubatka, Peter"'

5. Carotenoids in Cancer Metastasis—Status Quo and Outlook

Author

Koklesova, Lenka, primary, Liskova, Alena, additional, Samec, Marek, additional, Zhai, Kevin, additional, Abotaleb, Mariam, additional, Ashrafizadeh, Milad, additional, Brockmueller, Aranka, additional, Shakibaei, Mehdi, additional, Biringer, Kamil, additional, Bugos, Ondrej, additional, Najafi, Masoud, additional, Golubnitschaja, Olga, additional, Büsselberg, Dietrich, additional, and Kubatka, Peter, additional

Published
2020
Full Text
View/download PDF

7. Role of microRNA/Epithelial-to-Mesenchymal Transition Axis in the Metastasis of Bladder Cancer

Author

Ashrafizadeh, Milad, primary, Hushmandi, Kiavash, additional, Hashemi, Mehrdad, additional, Akbari, Mohammad Esmaeil, additional, Kubatka, Peter, additional, Raei, Mehdi, additional, Koklesova, Lenka, additional, Shahinozzaman, Md, additional, Mohammadinejad, Reza, additional, Najafi, Masoud, additional, Sethi, Gautam, additional, Kumar, Alan Prem, additional, and Zarrabi, Ali, additional

Published
2020
Full Text
View/download PDF

15. Fluctuations of Histone Chemical Modifications in Breast, Prostate, and Colorectal Cancer: An Implication of Phytochemicals as Defenders of Chromatin Equilibrium

Author

Samec, Marek, primary, Liskova, Alena, additional, Koklesova, Lenka, additional, Mestanova, Veronika, additional, Franekova, Maria, additional, Kassayova, Monika, additional, Bojkova, Bianka, additional, Uramova, Sona, additional, Zubor, Pavol, additional, Janikova, Katarina, additional, Danko, Jan, additional, Samuel, Samson, additional, Büsselberg, Dietrich, additional, and Kubatka, Peter, additional

Published
2019
Full Text
View/download PDF

17. DNA Methylation Status in Cancer Disease: Modulations by Plant-Derived Natural Compounds and Dietary Interventions

Author

Jasek, Karin, primary, Kubatka, Peter, additional, Samec, Marek, additional, Liskova, Alena, additional, Smejkal, Karel, additional, Vybohova, Desanka, additional, Bugos, Ondrej, additional, Biskupska-Bodova, Kristina, additional, Bielik, Tibor, additional, Zubor, Pavol, additional, Danko, Jan, additional, Adamkov, Marian, additional, Kwon, Taeg Kyu, additional, and Büsselberg, Dietrich, additional

Published
2019
Full Text
View/download PDF

19. Flavonoids and Their Anti-Diabetic Effects: Cellular Mechanisms and Effects to Improve Blood Sugar Levels.

Author

Al-Ishaq RK, Abotaleb M, Kubatka P, Kajo K, and Büsselberg D

Subjects
Animals, Blood Glucose drug effects, Diabetes Mellitus blood, Diabetes Mellitus metabolism, Humans, Lipogenesis drug effects, Diabetes Mellitus drug therapy, Flavonoids therapeutic use, Hypoglycemic Agents therapeutic use
Abstract

Diabetes mellitus (DM) is a prevailing global health metabolic disorder, with an alarming incidence rate and a huge burden on health care providers. DM is characterized by the elevation of blood glucose due either to a defect in insulin synthesis, secretion, binding to receptor, or an increase of insulin resistance. The internal and external factors such as obesity, urbanizations, and genetic mutations could increase the risk of developing DM. Flavonoids are phenolic compounds existing as secondary metabolites in fruits and vegetables as well as fungi. Their structure consists of 15 carbon skeletons and two aromatic rings (A and B) connected by three carbon chains. Flavonoids are furtherly classified into 6 subclasses: flavonols, flavones, flavanones, isoflavones, flavanols, and anthocyanidins. Naturally occurring flavonoids possess anti-diabetic effects. As in vitro and animal model's studies demonstrate, they have the ability to prevent diabetes and its complications. The aim of this review is to summarize the current knowledge addressing the antidiabetic effects of dietary flavonoids and their underlying molecular mechanisms on selected pathways: Glucose transporter, hepatic enzymes, tyrosine kinase inhibitor, AMPK, PPAR, and NF-κB. Flavonoids improve the pathogenesis of diabetes and its complications through the regulation of glucose metabolism, hepatic enzymes activities, and a lipid profile. Most studies illustrate a positive role of specific dietary flavonoids on diabetes, but the mechanisms of action and the side effects need more clarification. Overall, more research is needed to provide a better understanding of the mechanisms of diabetes treatment using flavonoids., Competing Interests: The authors declare no conflicts of interest.

Published
2019
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results