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Your search keyword '"Free fatty acid receptor 1"' showing total 18 results

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18 results on '"Free fatty acid receptor 1"'

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1. Exploration of phenylpropanoic acids as agonists of the free fatty acid receptor 4 (FFA4): Identification of an orally efficacious FFA4 agonist.

2. Quercetin-3-oleoyl derivatives as new GPR40 agonists: Molecular docking studies and functional evaluation

3. Design, synthesis and biological evaluation of indane derived GPR40 agoPAMs

4. Design, synthesis and biological activity of deuterium-based FFA1 agonists with improved pharmacokinetic profiles

5. Synthesis, biological evaluation, and molecular docking investigation of benzhydrol- and indole-based dual PPAR-γ/FFAR1 agonists

6. Discovery of N -arylpyrroles as agonists of GPR120 for the treatment of type II diabetes

7. Discovery of a novel potent GPR40 full agonist

8. FFAR1/GPR40: One target, different binding sites, many agonists, no drugs, but a continuous and unprofitable tug-of-war between ligand lipophilicity, activity, and toxicity

9. GPR40 agonists for the treatment of type 2 diabetes mellitus: The biological characteristics and the chemical space

10. Discovery of the imidazole-derived GPR40 agonist AM-3189

11. Phenoxymethyl 1,3-oxazoles and 1,2,4-oxadiazoles as potent and selective agonists of free fatty acid receptor 1 (GPR40)

12. Recent developments in the discovery of FFA1 receptor agonists as novel oral treatment for type 2 diabetes mellitus

13. Discovery of novel orally bioavailable GPR40 agonists

14. AMG 837: A potent, orally bioavailable GPR40 agonist

15. Discovery of 5-aryloxy-2,4-thiazolidinediones as potent GPR40 agonists

16. Synthesis and SAR of 1,2,3,4-tetrahydroisoquinolin-1-ones as novel G-protein-coupled receptor 40 (GPR40) antagonists

17. Discovery of diacylphloroglucinols as a new class of GPR40 (FFAR1) agonists

18. Solid phase synthesis and SAR of small molecule agonists for the GPR40 receptor

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