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Start Over Author "Godbout C" Journal bioorganic & medicinal chemistry letters
4 results on '"Godbout C"'

1. Structure–Activity Relationship of Biaryl Acylsulfonamide Analogues on the Human EP3 Prostanoid Receptor

Author

Gallant, M., primary, Carrière, M.C., additional, Chateauneuf, A., additional, Denis, D., additional, Gareau, Y., additional, Godbout, C., additional, Greig, G., additional, Juteau, H., additional, Lachance, N., additional, Lacombe, P., additional, Lamontagne, S., additional, Metters, K.M., additional, Rochette, C., additional, Ruel, R., additional, Slipetz, D., additional, Sawyer, N., additional, Tremblay, N., additional, and Labelle, M., additional

Published
2002
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4. Structure–Activity Relationship of Biaryl Acylsulfonamide Analogues on the Human EP3 Prostanoid Receptor

Author

Gallant, M., Carrière, M.C., Chateauneuf, A., Denis, D., Gareau, Y., Godbout, C., Greig, G., Juteau, H., Lachance, N., Lacombe, P., Lamontagne, S., Metters, K.M., Rochette, C., Ruel, R., Slipetz, D., Sawyer, N., Tremblay, N., and Labelle, M.

Subjects
*PROSTANOIDS, *LIGANDS (Biochemistry)
Abstract

Potent and selective ligands for the human EP3 prostanoid receptor are described. Biaryl compounds bearing a tethered ortho substituted acidic moiety were identified as potent EP3 antagonists based on the SAR described herein. The binding affinity of key compounds on all eight human prostanoid receptors is reported. [Copyright &y& Elsevier]

Published
2002
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