25 results on '"Medina, Julio C."'
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2. Discovery of the imidazole-derived GPR40 agonist AM-3189
3. Novel halogenated sulfonamides inhibit the growth of multidrug resistant MCF-7/ADR cancer cells
4. Synthesis and SAR study of potent and selective PI3Kδ inhibitors
5. Optimization beyond AMG 232: Discovery and SAR of sulfonamides on a piperidinone scaffold as potent inhibitors of the MDM2-p53 protein–protein interaction
6. Solving time-dependent CYP3A4 inhibition for a series of indole-phenylacetic acid dual antagonists of the PGD2 receptors CRTH2 and DP
7. Structure-assisted discovery of the first non-retinoid ligands for Retinol-Binding Protein 4
8. Discovery and optimization of 5-(2-((1-(phenylsulfonyl)-1,2,3,4-tetrahydroquinolin-7-yl)oxy)pyridin-4-yl)-1,2,4-oxadiazoles as novel gpr119 agonists
9. Discovery and optimization of N-(3-(1,3-dioxo-2,3-dihydro-1H-pyrrolo[3,4-c]pyridin-4-yloxy)phenyl)benzenesulfonamides as novel GPR119 agonists
10. Discovery and optimization of arylsulfonyl 3-(pyridin-2-yloxy)anilines as novel GPR119 agonists
11. Phenylalanine derivatives as GPR142 agonists for the treatment of Type II diabetes
12. Discovery and optimization of a novel series of GPR142 agonists for the treatment of type 2 diabetes mellitus
13. Optimization of phenylacetic acid derivatives for balanced CRTH2 and DP dual antagonists
14. AMG 837: A potent, orally bioavailable GPR40 agonist
15. Optimization of phenylacetic acid derivatives for CRTH2 and DP selective antagonism
16. Discovery of potent and specific CXCR3 antagonists
17. Optimization of triazoles as novel and potent nonphlorizin SGLT2 inhibitors
18. Identification of piperazine-bisamide GHSR antagonists for the treatment of obesity
19. Imidazo-pyrazine derivatives as potent CXCR3 antagonists
20. Design and optimization of imidazole derivatives as potent CXCR3 antagonists
21. Optimization of the heterocyclic core of the quinazolinone-derived CXCR3 antagonists
22. Corrigendum to “Phenylalanine derivatives as GPR142 agonists for the treatment of Type II diabetes” [Bioorg. Med. Chem. Lett. 22 (2012) 6218–6223]
23. Optimization of 2-aminothiazole derivatives as CCR4 antagonists
24. Discovery and optimization of a novel series of liver X receptor-α agonists
25. Novel antineoplastic agents with efficacy against multidrug resistant tumor cells
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