1. Membrane destabilization and pore formation induced by the Synechocystis IM30 protein
- Author
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Benedikt Junglas, Amelie Axt, Carmen Siebenaller, Hilal Sonel, Nadja Hellmann, Stefan A.L. Weber, and Dirk Schneider
- Subjects
Chloroplasts ,Biophysics ,Synechocystis ,Membrane Proteins ,Membrane Fusion ,Thylakoids - Abstract
The inner membrane-associated protein of 30 kDa (IM30) is essential in chloroplasts and cyanobacteria. The spatio-temporal cellular localization of the protein appears to be highly dynamic and triggered by internal as well as external stimuli, mainly light intensity. The soluble fraction of the protein is localized in the cyanobacterial cytoplasm or the chloroplast stroma, respectively. Additionally, the protein attaches to the thylakoid membrane as well as to the chloroplast inner envelope or the cyanobacterial cytoplasmic membrane, respectively, especially under conditions of membrane stress. IM30 is involved in thylakoid membrane biogenesis and/or maintenance, where it either stabilizes membranes and/or triggers membrane-fusion processes. These apparently contradicting functions have to be tightly controlled and separated spatiotemporally in chloroplasts and cyanobacteria. IM30's fusogenic activity depends on Mg
- Published
- 2022