1. Dynamic Simulations of Cell Migration with Applications to Brain Development
- Author
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Alexander Schug, Claude Sinner, Ines Reinartz, Bernadett Bosze, and Steffen Scholpp
- Subjects
Cell signaling ,Multicellular organism ,Macroscopic scale ,Embryogenesis ,Biophysics ,Cell migration ,Biology ,Stem cell ,Microscopic scale ,Morphogen ,Cell biology - Abstract
The early stages of embryogenesis are the most fundamental stages in the development of any multicellular organism. A plethora of cell signaling modes regulate the migration and differentiation of stem cells into various tissue types, which later merge into complete organs. Here, form-giving substances, so-called morphogens, coordinate the development of the body axis. These early stages are highly interesting from a physical standpoint, as one has to consider the interplay between cell migration on a macroscopic scale and morphogen transport on a microscopic scale.
- Published
- 2016
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