1. Diagnostic value and safety of color doppler ultrasound-guided transthoracic core needle biopsy of thoracic disease
- Author
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Fang Liu, Xueqin Chen, Ning Xu, Weina Huang, Tianwen Lai, Shiyi He, Libin Chen, and Linfeng Wang
- Subjects
Male ,Core needle ,medicine.medical_specialty ,Lung Neoplasms ,Thoracic disease ,Biopsy ,Biophysics ,Biopsy guns ,Mediastinal Neoplasms ,Biochemistry ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Transthoracic Core Needle ,medicine ,Humans ,Ultrasonography, Doppler, Color ,Lung ,Molecular Biology ,Research Articles ,Aged ,medicine.diagnostic_test ,business.industry ,Mediastinum ,Cell Biology ,Color doppler ultrasound ,Color doppler ,Middle Aged ,medicine.anatomical_structure ,Fine-needle aspiration ,030228 respiratory system ,Female ,Biopsy, Large-Core Needle ,Color Doppler ultrasound ,Radiology ,business ,Research Article - Abstract
Objective: The aim of the present study was to explore the diagnostic value and safety of color Doppler ultrasound (US)-guided transthoracic core needle biopsy (CNB) of peripheral lung, chest wall and mediastinal lesions using automated biopsy guns. Materials and methods: We analyzed clinical and image data, histopathologic and microbiologic details and complications from 121 patients with peripheral lung, chest wall and mediastinal lesions who underwent color Doppler US-guided transthoracic CNB in Ningbo First Hospital between January 2015 and June 2018. Results: Color Doppler US-guided transthoracic CNB performed with a freehand technique using automated biopsy guns had a sensitivity of 93.94%, a specificity of 100%, a positive predictive value of 100%, a negative predictive value of 78.57%, and a diagnostic accuracy of 95.04%. Lesion size did not affect the diagnostic rate (P=0.40). No serious complications of the procedure were noted. Conclusion: Color Doppler US-guided transthoracic CNB of peripheral lung, chest wall and mediastinal lesions is a safe and inexpensive procedure. The diagnostic accuracy of color Doppler US-guided transthoracic CNB was higher than that of color Doppler US-guided transthoracic fine needle aspiration biopsy (FNAB).
- Published
- 2019
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