1. Efeito Antibacteriano e Antifúngico de Extratos Etanólico, Hexânico e Metanólico a Partir de Folhas de Kalanchoe pinnata (Lam.) Pers (Malva Corama) Contra Cepas Multi-Resistentes a Drogas
- Author
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Lívia Maria Garcia Leandro, Pedro Everson Alexandre de Aquino, Amanda Aragão Alves, Vivianne Inácio Leite, Francisco Adelvane de Paulo Rodrigues, Gabriel Gusmão Grisi Rocha, Priscilla Caracas Vieira de Sousa, Roberta Oliveira da Costa, Saulo Relison Tintino, Ana Luiza de Aguiar Rocha Martin, Raul de S. Andreza, Bruna Suellen Pereira, Cícera D. M Oliveira, Paloma de Souza Santana, and Fernando Gomes Figueredo
- Subjects
biology ,Traditional medicine ,medicine.drug_class ,Antibiotics ,Pharmaceutical Science ,Kalanchoe ,Antimicrobial ,biology.organism_classification ,Microbiology ,Minimum inhibitory concentration ,Antibacterianos ,Complementary and alternative medicine ,Phytochemical ,Bactérias ,Candida krusei ,medicine ,Pharmacology (medical) ,Fungos ,Candida albicans ,Medicinal plants - Abstract
The infections caused by bacteria and fungi, as well as the subsequent resistance of these microorganisms continue with high incidencesthus studies of medicinal plants and their combination with conventional therapy, are becoming essential. This study examined the antibacterial, antifungal and modifier of resistance to antibiotics and antifungal extracts of ethanol, hexane and methanol from the leaves of Kalanchoe pinnata, used in folk medicine. The phytochemical was performed qualitatively by visual observation of color changes and formation of precipitates after addition of specific reagents, such as ferric chloride (Fecl310%) sodium hydroxide (NaOH10%), hydrochloric acid (HCl 1%), acid acetic acid 5%, ammonium hydroxide (NH4OH 10%), chloroform and reagent Draggendorff 10%. The analysis for antimicrobial activity was through the microdilution test for determination of minimum inhibitory concentration (MIC) and modifying the action of antibiotics (gentamicin and amikacin) and antifungals (ketoconazole and fluconazole) in association with the extracts. The phytochemicals assays indicated the presence of secondary metabolites such as flavonoids, alkaloids and flabobênicos tannins. In assessing the MIC results were obtained
- Published
- 2016
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