38 results on '"Aifantis, Iannis"'
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2. STAT3 supports experimental K-RasG12D–induced murine myeloproliferative neoplasms dependent on serine phosphorylation
3. Notch signaling: switching an oncogene to a tumor suppressor
4. Non-Classical Monocyte Abundance Is an Independent Adverse Risk Factor for Relapse in Pediatric B-ALL
5. Modulation of RNA Splicing Enhances Response to BCL2 Inhibition in Acute Myeloid Leukemia
6. Coactivation of NF-κB and Notch signaling is sufficient to induce B-cell transformation and enables B-myeloid conversion
7. Innate Immune Signaling Suppresses Acute Leukemia By Modifying MYC Oncogenic Activity
8. Dll1 and Dll4 Notch Ligands Prime T Cell Alloimmunity and Are Expressed in Non-Overlapping Populations of Fibroblastic Stromal Cells in Spleen and Lymph Nodes at the Onset of Gvhd
9. Oncogenic-Drivers Dictate Immune Responses to Control Disease Progression in Acute Myeloid Leukaemia
10. Therapeutic Targeting of an RNA Splicing Factor Network for the Treatment of Myeloid Neoplasms
11. Donor T Cells Require Notch Signals but Not Alloantigen Presentation from Specialized Secondary Lymphoid Organ Fibroblasts to Drive Graft-Versus-Host Disease
12. The Impact of 3D Chromosomal Topology in Acute Leukemia
13. Coactivation of NF-?B and Notch signaling is sufficient to induce B-cell transformation and enables B-myeloid conversion
14. Deconvoluting Clonal and Cellular Architecture in IDH-Mutant Acute Myeloid Leukemia
15. The Genomic and Transcriptomic Landscape of Myeloid Sarcoma and Associated Acute Myeloid Leukemia
16. Clinical and Prognostic Implications of WT1Mutations in De Novo and Relapsed Acute Myeloid Leukemia
17. Stroma-Driven Notch2 Signaling Controls Naïve B Cell Fate By Regulating Microenvironmental Positioning within the Spleen
18. Expression of an Oncogenic ERG isoform Characterizes a Distinct Subtype of B-Progenitor Acute Lymphoblastic Leukemia
19. SRSF2 Mutations Impair Hematopoietic Differentiation By Altering Exonic Splicing Enhancer Preference
20. An Oncogene-Regulated Epigenetic Switch in T Cell Acute Lymphoblastic Leukemia
21. DNA Hydroxymethylation Profiling Reveals That WT1 Mutations Result in Loss of TET2 Function in Acute Myeloid Leukemia
22. Epigenetic Profiling Of Leukemia Stem Cells In a Model Of TET2/FLT3-Mutant AML
23. New Design Of Human T-ALL Transplantation In NSG Mice Uncovers The Major Role Of CD31/PECAM1 In The Central Nervous System Infiltration
24. Conditional Deletion of Asxl1 Results in Myelodysplasia
25. A Role for TET2 Mutations in Paroxysmal Nocturnal Hemoglobinuria (PNH)
26. The Notch Signaling Pathway as a Suppressor of Myeloid Transformation
27. ASXL1 Mutations Promote Myeloid Transformation Through Inhibition of PRC2-Mediated Gene Repression
28. Evaluating Clonal Dominance in a Murine Knock-in Model of Jak2V617F MPN
29. Inhibition of NOTCH1 Signaling and Glucocorticoid Therapy in T-ALL
30. Knockdown of CCR7 or Its Ligands Causes a Loss of Central Nervous System Involvement in Notch1 Induced T-ALL
31. FBW7 E3-Ligase Mutations Are Associated with T Cell Leukemia.
32. Notch1 promotes survival of E2A-deficient T cell lymphomas through pre–T cell receptor–dependent and –independent mechanisms
33. High ORM1Expression Marks a Subset of Genetically Adverse-Risk B-ALL Characterized By MDSC Enrichment, T-Cell Dysfunction, and Inferior Overall Survival
34. Expression of an Oncogenic ERGisoform Characterizes a Distinct Subtype of B-Progenitor Acute Lymphoblastic Leukemia
35. SRSF2Mutations Impair Hematopoietic Differentiation By Altering Exonic Splicing Enhancer Preference
36. DNA Hydroxymethylation Profiling Reveals That WT1Mutations Result in Loss of TET2 Function in Acute Myeloid Leukemia
37. A Role for TET2Mutations in Paroxysmal Nocturnal Hemoglobinuria (PNH)
38. ASXL1Mutations Promote Myeloid Transformation Through Inhibition of PRC2-Mediated Gene Repression
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